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Muscular involvement of extranodal natural killer/T cell lymphoma misdiagnosed as polymyositis: A case report and review of literature.
Liu, Li-Hui; Huang, Qing; Liu, Yun-Hai; Yang, Jie; Fu, Han; Jin, Lin.
Afiliación
  • Liu LH; Department of Neurology, Xiangya Hospital of Central South University, Changsha 410008, Hunan Province, China.
  • Huang Q; Department of Neurology, Xiangya Hospital of Central South University, Changsha 410008, Hunan Province, China.
  • Liu YH; Department of Neurology, Xiangya Hospital of Central South University, Changsha 410008, Hunan Province, China.
  • Yang J; Department of Neurology, Xiangya Hospital of Central South University, Changsha 410008, Hunan Province, China.
  • Fu H; Department of Dermatology, Xiangya Hospital of Central South University, Changsha 410008, Hunan Province, China.
  • Jin L; Department of Neurology, Xiangya Hospital of Central South University, Changsha 410008, Hunan Province, China.
World J Clin Cases ; 8(5): 963-970, 2020 Mar 06.
Article en En | MEDLINE | ID: mdl-32190634
BACKGROUND: Natural killer (NK)/T cell lymphoma is a rare and highly aggressive malignant tumor, and is a special form of non-Hodgkin's lymphoma. Although extranodal involvement is frequently found in tissues such as the skin, testicular and gastrointestinal tract etc, its presence in skeletal muscle has scarcely been reported in the literature. CASE SUMMARY: We report a case of extranodal NK/T cell lymphoma with muscle swelling as the first clinical manifestation. A 42-year-old man, who initially presented with localized swelling in the double lower extremities, demonstrated gradual facial and eyelid swelling, and his imaging results showed multiple sites of muscle damage throughout the body. The final pathological results suggested NK/T cell lymphoma, and immunohistochemistry showed CD20 (-), CD3Ɛ (+), CD30 (+), CD56 (-), EBER (+), Ki67 (60%), TIA-1 (+) and CD68 (±) staining. The muscle swelling significantly improved after treatment with chemotherapy regimens. CONCLUSION: This disease is difficult to diagnose and highly invasive, and should be included in the differential diagnosis of unexplained muscle swelling.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: World J Clin Cases Año: 2020 Tipo del documento: Article País de afiliación: China Pais de publicación: Estados Unidos
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: World J Clin Cases Año: 2020 Tipo del documento: Article País de afiliación: China Pais de publicación: Estados Unidos