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Progress in Neuroengineering for brain repair: New challenges and open issues.
Panuccio, Gabriella; Semprini, Marianna; Natale, Lorenzo; Buccelli, Stefano; Colombi, Ilaria; Chiappalone, Michela.
Afiliación
  • Panuccio G; Department of Neuroscience and Brain Technologies (NBT), Istituto Italiano di Tecnologia (IIT), Genova, Italy.
  • Semprini M; Rehab Technologies, Istituto Italiano di Tecnologia, Genova, Italy.
  • Natale L; iCub Facility, Istituto Italiano di Tecnologia, Genova, Italy.
  • Buccelli S; Department of Neuroscience and Brain Technologies (NBT), Istituto Italiano di Tecnologia (IIT), Genova, Italy.
  • Colombi I; Rehab Technologies, Istituto Italiano di Tecnologia, Genova, Italy.
  • Chiappalone M; Dipartimento di Neuroscienze, riabilitazione, oftalmologia, genetica e scienze materno-infantili (DINOGMI), University of Genova, Genova, Italy.
Brain Neurosci Adv ; 2: 2398212818776475, 2018.
Article en En | MEDLINE | ID: mdl-32166141
BACKGROUND: In recent years, biomedical devices have proven to be able to target also different neurological disorders. Given the rapid ageing of the population and the increase of invalidating diseases affecting the central nervous system, there is a growing demand for biomedical devices of immediate clinical use. However, to reach useful therapeutic results, these tools need a multidisciplinary approach and a continuous dialogue between neuroscience and engineering, a field that is named neuroengineering. This is because it is fundamental to understand how to read and perturb the neural code in order to produce a significant clinical outcome. RESULTS: In this review, we first highlight the importance of developing novel neurotechnological devices for brain repair and the major challenges expected in the next years. We describe the different types of brain repair strategies being developed in basic and clinical research and provide a brief overview of recent advances in artificial intelligence that have the potential to improve the devices themselves. We conclude by providing our perspective on their implementation to humans and the ethical issues that can arise. CONCLUSIONS: Neuroengineering approaches promise to be at the core of future developments for clinical applications in brain repair, where the boundary between biology and artificial intelligence will become increasingly less pronounced.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Aspecto: Ethics Idioma: En Revista: Brain Neurosci Adv Año: 2018 Tipo del documento: Article País de afiliación: Italia Pais de publicación: Estados Unidos

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Aspecto: Ethics Idioma: En Revista: Brain Neurosci Adv Año: 2018 Tipo del documento: Article País de afiliación: Italia Pais de publicación: Estados Unidos