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Combined Therapy of AXL and HDAC Inhibition Reverses Mesenchymal Transition in Diffuse Intrinsic Pontine Glioma.
Meel, Michaël H; de Gooijer, Mark C; Metselaar, Dennis S; Sewing, A Charlotte P; Zwaan, Kenn; Waranecki, Piotr; Breur, Marjolein; Buil, Levi C M; Lagerweij, Tonny; Wedekind, Laurine E; Twisk, Jos W R; Koster, Jan; Hashizume, Rintaro; Raabe, Eric H; Montero Carcaboso, Ángel; Bugiani, Marianna; Phoenix, Timothy N; van Tellingen, Olaf; van Vuurden, Dannis G; Kaspers, Gertjan J L; Hulleman, Esther.
Afiliación
  • Meel MH; Departments of Pediatric Oncology/Hematology, Cancer Center Amsterdam, Amsterdam University Medical Centers, Amsterdam, the Netherlands.
  • de Gooijer MC; Princess Máxima Center for Pediatric Oncology, Utrecht, the Netherlands.
  • Metselaar DS; Division of Pharmacology/Mouse Cancer Clinic, The Netherlands Cancer Institute, Amsterdam, the Netherlands.
  • Sewing ACP; Departments of Pediatric Oncology/Hematology, Cancer Center Amsterdam, Amsterdam University Medical Centers, Amsterdam, the Netherlands.
  • Zwaan K; Princess Máxima Center for Pediatric Oncology, Utrecht, the Netherlands.
  • Waranecki P; Departments of Pediatric Oncology/Hematology, Cancer Center Amsterdam, Amsterdam University Medical Centers, Amsterdam, the Netherlands.
  • Breur M; Departments of Pediatric Oncology/Hematology, Cancer Center Amsterdam, Amsterdam University Medical Centers, Amsterdam, the Netherlands.
  • Buil LCM; Departments of Pediatric Oncology/Hematology, Cancer Center Amsterdam, Amsterdam University Medical Centers, Amsterdam, the Netherlands.
  • Lagerweij T; Princess Máxima Center for Pediatric Oncology, Utrecht, the Netherlands.
  • Wedekind LE; Department of Pathology, Amsterdam University Medical Centers, Amsterdam, the Netherlands.
  • Twisk JWR; Division of Pharmacology/Mouse Cancer Clinic, The Netherlands Cancer Institute, Amsterdam, the Netherlands.
  • Koster J; Department of Neurosurgery, Neuro-oncology Research Group, Cancer Center Amsterdam, Amsterdam University Medical Centers, Amsterdam, the Netherlands.
  • Hashizume R; Department of Neurosurgery, Neuro-oncology Research Group, Cancer Center Amsterdam, Amsterdam University Medical Centers, Amsterdam, the Netherlands.
  • Raabe EH; Department of Epidemiology and Biostatistics, Amsterdam University Medical Centers, Amsterdam, the Netherlands.
  • Montero Carcaboso Á; Department of Oncogenomics, Amsterdam University Medical Centers, Amsterdam, the Netherlands.
  • Bugiani M; Departments of Neurological Surgery and Molecular Genetics, Northwestern University Feinberg School of Medicine, Chicago, Illinois.
  • Phoenix TN; Division of Pediatric Oncology, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, Maryland.
  • van Tellingen O; Preclinical Therapeutics and Drug Delivery Research Program, Department of Oncology, Hospital Sant Joan de Déu Barcelona, Spain.
  • van Vuurden DG; Department of Pathology, Amsterdam University Medical Centers, Amsterdam, the Netherlands.
  • Kaspers GJL; Division of Pharmaceutical Sciences, College of Pharmacy, University of Cincinnati/Research in Patient Services, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio.
  • Hulleman E; Division of Pharmacology/Mouse Cancer Clinic, The Netherlands Cancer Institute, Amsterdam, the Netherlands.
Clin Cancer Res ; 26(13): 3319-3332, 2020 07 01.
Article en En | MEDLINE | ID: mdl-32165429
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Proteínas Proto-Oncogénicas / Proteínas Tirosina Quinasas Receptoras / Inhibidores de Proteínas Quinasas / Inhibidores de Histona Desacetilasas / Glioma Pontino Intrínseco Difuso / Histona Desacetilasas Tipo de estudio: Etiology_studies Límite: Animals / Humans Idioma: En Revista: Clin Cancer Res Asunto de la revista: NEOPLASIAS Año: 2020 Tipo del documento: Article País de afiliación: Países Bajos Pais de publicación: Estados Unidos
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Proteínas Proto-Oncogénicas / Proteínas Tirosina Quinasas Receptoras / Inhibidores de Proteínas Quinasas / Inhibidores de Histona Desacetilasas / Glioma Pontino Intrínseco Difuso / Histona Desacetilasas Tipo de estudio: Etiology_studies Límite: Animals / Humans Idioma: En Revista: Clin Cancer Res Asunto de la revista: NEOPLASIAS Año: 2020 Tipo del documento: Article País de afiliación: Países Bajos Pais de publicación: Estados Unidos