Oriented Immobilization on Gold Nanoparticles of a Recombinant Therapeutic Zymogen.

Dosadina, Elina; Agyeiwaa, Celetia; Ferreira, William; Cutting, Simon; Jibawi, Abdullah; Ferrari, Enrico; Soloviev, Mikhail

Dosadina, Elina; Agyeiwaa, Celetia; Ferreira, William; Cutting, Simon; Jibawi, Abdullah; Ferrari, Enrico; Soloviev, Mikhail.

Afiliación

Dosadina E; Centre for Biomedical Sciences, School of Biological Sciences, Royal Holloway University of London, Egham, Surrey, UK.
Agyeiwaa C; Centre for Biomedical Sciences, School of Biological Sciences, Royal Holloway University of London, Egham, Surrey, UK.
Ferreira W; Centre for Biomedical Sciences, School of Biological Sciences, Royal Holloway University of London, Egham, Surrey, UK.
Cutting S; Centre for Biomedical Sciences, School of Biological Sciences, Royal Holloway University of London, Egham, Surrey, UK.
Jibawi A; Ashford and St. Peter's Hospitals NHS Foundation Trust, Surrey, UK.
Ferrari E; College of Science, School of Life Sciences, University of Lincoln, Brayford Pool, Lincoln, Lincolnshire, UK.
Soloviev M; Centre for Biomedical Sciences, Department of Biological Sciences, Royal Holloway University of London, Egham, Surrey, UK. mikhail.soloviev@rhul.ac.uk.

Methods Mol Biol ; 2118: 213-225, 2020.

Article en En | MEDLINE | ID: mdl-32152982

Asunto(s)

Glutatión Transferasa/genética; Oro/química; Metaloendopeptidasas/genética; Activadores Plasminogénicos/farmacología; Proteínas Recombinantes/farmacología; Enzimas Inmovilizadas/química; Enzimas Inmovilizadas/farmacología; Fibrinógeno/metabolismo; Glutatión Transferasa/química; Humanos; Nanopartículas del Metal; Metaloendopeptidasas/química; Modelos Moleculares; Activadores Plasminogénicos/química; Conformación Proteica; Pliegue de Proteína; Proteínas Recombinantes/química

Palabras clave

Experimental design; Gold nanoparticles; Oriented immobilization; Plasminogen activator; Protein function; Protein immobilization; Protein stability; Staphylokinase; Therapeutic protein

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Proteínas Recombinantes / Metaloendopeptidasas / Activadores Plasminogénicos / Glutatión Transferasa / Oro Tipo de estudio: Prognostic_studies Límite: Humans Idioma: En Revista: Methods Mol Biol Asunto de la revista: BIOLOGIA MOLECULAR Año: 2020 Tipo del documento: Article País de afiliación: Reino Unido Pais de publicación: Estados Unidos

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