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HDAC6 inhibition promotes α-tubulin acetylation and ameliorates CMT2A peripheral neuropathy in mice.
Picci, Cristina; Wong, Victor S C; Costa, Christopher J; McKinnon, Marion C; Goldberg, David C; Swift, Michelle; Alam, Nazia M; Prusky, Glen T; Shen, Sida; Kozikowski, Alan P; Willis, Dianna E; Langley, Brett.
Afiliación
  • Picci C; The Burke Neurological Institute, White Plains, NY, 10605, USA; Brain and Mind Research Institute, Weill Cornell Medicine, New York, NY 10065, USA; School of Health, The University of Waikato, Private Bag 3105, Hamilton, New Zealand. Electronic address: cpicci@waikato.ac.nz.
  • Wong VSC; The Burke Neurological Institute, White Plains, NY, 10605, USA; Brain and Mind Research Institute, Weill Cornell Medicine, New York, NY 10065, USA.
  • Costa CJ; The Burke Neurological Institute, White Plains, NY, 10605, USA.
  • McKinnon MC; School of Health, The University of Waikato, Private Bag 3105, Hamilton, New Zealand.
  • Goldberg DC; The Burke Neurological Institute, White Plains, NY, 10605, USA.
  • Swift M; The Burke Neurological Institute, White Plains, NY, 10605, USA.
  • Alam NM; The Burke Neurological Institute, White Plains, NY, 10605, USA; Department of Physiology and Biophysics, Weill Cornell Medicine, New York, NY 10065, USA.
  • Prusky GT; The Burke Neurological Institute, White Plains, NY, 10605, USA; Department of Physiology and Biophysics, Weill Cornell Medicine, New York, NY 10065, USA.
  • Shen S; Department of Medicinal Chemistry and Pharmacognosy, College of Pharmacy, University of Illinois at Chicago, Chicago, IL 60612, USA.
  • Kozikowski AP; StarWise Therapeutics LLC, 2020 N Lincoln Park West, Chicago, IL 60614, USA.
  • Willis DE; The Burke Neurological Institute, White Plains, NY, 10605, USA; Brain and Mind Research Institute, Weill Cornell Medicine, New York, NY 10065, USA. Electronic address: diw2004@med.cornell.edu.
  • Langley B; The Burke Neurological Institute, White Plains, NY, 10605, USA; Brain and Mind Research Institute, Weill Cornell Medicine, New York, NY 10065, USA; School of Health, The University of Waikato, Private Bag 3105, Hamilton, New Zealand. Electronic address: blangley@waikato.ac.nz.
Exp Neurol ; 328: 113281, 2020 06.
Article en En | MEDLINE | ID: mdl-32147437
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Quinolinas / Tubulina (Proteína) / Benzamidas / Inhibidores de Histona Desacetilasas / Histona Desacetilasa 6 Tipo de estudio: Prognostic_studies Límite: Animals Idioma: En Revista: Exp Neurol Año: 2020 Tipo del documento: Article Pais de publicación: Estados Unidos
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Quinolinas / Tubulina (Proteína) / Benzamidas / Inhibidores de Histona Desacetilasas / Histona Desacetilasa 6 Tipo de estudio: Prognostic_studies Límite: Animals Idioma: En Revista: Exp Neurol Año: 2020 Tipo del documento: Article Pais de publicación: Estados Unidos