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FcRn overexpression in human cancer drives albumin recycling and cell growth; a mechanistic basis for exploitation in targeted albumin-drug designs.
Larsen, Maja Thim; Mandrup, Ole A; Schelde, Karen Kræmmer; Luo, Yonglun; Sørensen, Karina Dalsgaard; Dagnæs-Hansen, Frederik; Cameron, Jason; Stougaard, Magnus; Steiniche, Torben; Howard, Kenneth A.
Afiliación
  • Larsen MT; Interdisciplinary Nanoscience Center (iNANO), Department of Molecular Biology and Genetics, Aarhus University, DK-8000 Aarhus C, Denmark.
  • Mandrup OA; Interdisciplinary Nanoscience Center (iNANO), Department of Molecular Biology and Genetics, Aarhus University, DK-8000 Aarhus C, Denmark.
  • Schelde KK; Interdisciplinary Nanoscience Center (iNANO), Department of Molecular Biology and Genetics, Aarhus University, DK-8000 Aarhus C, Denmark.
  • Luo Y; Department of Biomedicine, Aarhus University, DK-8000 Aarhus C, Denmark; Lars Bolund Institute of Regenerative Medicine, BGI-Qingdao, BGI-Shenzhen, 518083 Shenzhen, China.
  • Sørensen KD; Department of Molecular Medicine, Aarhus University Hospital, Department of Clinical Medicine, Aarhus University, DK-8200 Aarhus N, Denmark.
  • Dagnæs-Hansen F; Department of Biomedicine, Aarhus University, DK-8000 Aarhus C, Denmark.
  • Cameron J; Albumedix Ltd, Castle Court, 59 Castle Boulevard, Nottingham NG7 1FD, United Kingdom.
  • Stougaard M; Department of Clinical Medicine, The Department of Pathology, Aarhus University Hospital, DK-8000 Aarhus C, Denmark.
  • Steiniche T; Department of Clinical Medicine, The Department of Pathology, Aarhus University Hospital, DK-8000 Aarhus C, Denmark.
  • Howard KA; Interdisciplinary Nanoscience Center (iNANO), Department of Molecular Biology and Genetics, Aarhus University, DK-8000 Aarhus C, Denmark. Electronic address: kenh@inano.au.dk.
J Control Release ; 322: 53-63, 2020 06 10.
Article en En | MEDLINE | ID: mdl-32145268

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Diseño de Fármacos / Neoplasias Límite: Animals / Humans Idioma: En Revista: J Control Release Asunto de la revista: FARMACOLOGIA Año: 2020 Tipo del documento: Article País de afiliación: Dinamarca Pais de publicación: Países Bajos

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Diseño de Fármacos / Neoplasias Límite: Animals / Humans Idioma: En Revista: J Control Release Asunto de la revista: FARMACOLOGIA Año: 2020 Tipo del documento: Article País de afiliación: Dinamarca Pais de publicación: Países Bajos