Protective role of berberine on ulcerative colitis through modulating enteric glial cells-intestinal epithelial cells-immune cells interactions.

Li, Heng; Fan, Chen; Lu, Huimin; Feng, Chunlan; He, Peilan; Yang, Xiaoqian; Xiang, Caigui; Zuo, Jianping; Tang, Wei

Li, Heng; Fan, Chen; Lu, Huimin; Feng, Chunlan; He, Peilan; Yang, Xiaoqian; Xiang, Caigui; Zuo, Jianping; Tang, Wei.

Afiliación

Li H; Laboratory of Anti-inflammation and Immunopharmacology, State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, China.
Fan C; School of Pharmacy, University of Chinese Academy of Sciences, Beijing 100049, China.
Lu H; Laboratory of Anti-inflammation and Immunopharmacology, State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, China.
Feng C; Laboratory of Anti-inflammation and Immunopharmacology, State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, China.
He P; School of Pharmacy, University of Chinese Academy of Sciences, Beijing 100049, China.
Yang X; Laboratory of Anti-inflammation and Immunopharmacology, State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, China.
Xiang C; Laboratory of Anti-inflammation and Immunopharmacology, State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, China.
Zuo J; Laboratory of Anti-inflammation and Immunopharmacology, State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, China.
Tang W; Laboratory of Anti-inflammation and Immunopharmacology, State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, China.

Acta Pharm Sin B ; 10(3): 447-461, 2020 Mar.

Article en En | MEDLINE | ID: mdl-32140391

Palabras clave

APCs, antigen-presenting cells; BDNF, brain-derived neurotrophic factor; BMDCs, bone marrow-derived dendritic cells; Berberine; CGRP, calcitonin gene-related peptide; DSS, dextran sulfate sodium; EGCs, enteric glial cells; ENS, enteric nervous system; Enteric glial cells; Enteric nervous system; GDNF, glial cell derived neurotrophic factor; GFAP, glial fibrillary acidic protein; IBD, inflammatory bowel diseases; IECs, intestinal epithelial cells; LMPC, lamina propria mononuclear cells; MAPK, mitogen-activated protein kinases; MLNs, mesenteric lymph nodes; MPO, myeloperoxidase; Mucosal inflammation; UC, ulcerative colitis; Ulcerative colitis; VIP, vasoactive intestinal polypeptide

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Acta Pharm Sin B Año: 2020 Tipo del documento: Article País de afiliación: China Pais de publicación: Países Bajos

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