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Associations Between Multiple Remote Mild TBIs and Objective Neuropsychological Functioning and Subjective Symptoms in Combat-Exposed Veterans.
Merritt, Victoria C; Jurick, Sarah M; Crocker, Laura D; Sullan, Molly J; Sakamoto, McKenna S; Davey, Delaney K; Hoffman, Samantha N; Keller, Amber V; Jak, Amy J.
Afiliación
  • Merritt VC; Research & Psychology Services, VA San Diego Healthcare System (VASDHS), San Diego, CA, USA.
  • Jurick SM; Research & Psychology Services, VA San Diego Healthcare System (VASDHS), San Diego, CA, USA.
  • Crocker LD; Center of Excellence for Stress and Mental Health, VASDHS, San Diego, CA, USA.
  • Sullan MJ; Research & Psychology Services, VA San Diego Healthcare System (VASDHS), San Diego, CA, USA.
  • Sakamoto MS; Center of Excellence for Stress and Mental Health, VASDHS, San Diego, CA, USA.
  • Davey DK; Research & Psychology Services, VA San Diego Healthcare System (VASDHS), San Diego, CA, USA.
  • Hoffman SN; Research & Psychology Services, VA San Diego Healthcare System (VASDHS), San Diego, CA, USA.
  • Keller AV; Research & Psychology Services, VA San Diego Healthcare System (VASDHS), San Diego, CA, USA.
  • Jak AJ; San Diego Joint Doctoral Program in Clinical Psychology, State University/University of California San Diego (SDSU/UCSD), San Diego, CA, USA.
Arch Clin Neuropsychol ; 35(5): 491-505, 2020 Jul 24.
Article en En | MEDLINE | ID: mdl-32128559
OBJECTIVE: The purpose of this study was to evaluate relationships between multiple mild traumatic brain injuries (mTBIs) and objective and subjective clinical outcomes in a sample of combat-exposed Veterans, adjusting for psychiatric distress and combat exposure. METHOD: In this cross-sectional study, 73 combat-exposed Iraq/Afghanistan Veterans were divided into three groups based on mTBI history: 0 mTBIs (n = 31), 1-2 mTBIs (n = 21), and 3+ mTBIs (n = 21). Veterans with mTBI were assessed, on average, 7.78 years following their most recent mTBI. Participants underwent neuropsychological testing and completed self-report measures assessing neurobehavioral, sleep, and pain symptoms. RESULTS: MANCOVAs adjusting for psychiatric distress and combat exposure showed no group differences on objective measures of attention/working memory, executive functioning, memory, and processing speed (all p's > .05; ηp2 = .00-.06). In contrast, there were significant group differences on neurobehavioral symptoms (p's = < .001-.036; ηp2 = .09-.43), sleep difficulties (p = .037; ηp2 = .09), and pain symptoms (p < .001; ηp2 = .21). Pairwise comparisons generally showed that the 3+ mTBI group self-reported the most severe symptoms, followed by comparable symptom reporting between the 0 and 1-2 mTBI groups. CONCLUSIONS: History of multiple, remote mTBIs is associated with elevated subjective symptoms but not objective neuropsychological functioning in combat-exposed Veterans. These results advance understanding of the long-term consequences of repetitive mTBI in this population and suggest that Veterans with 3+ mTBIs may especially benefit from tailored treatments aimed at ameliorating specific neurobehavioral, sleep, and pain symptoms.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Trastornos por Estrés Postraumático / Veteranos / Lesiones Traumáticas del Encéfalo Tipo de estudio: Diagnostic_studies / Observational_studies / Prevalence_studies / Risk_factors_studies Límite: Humans Idioma: En Revista: Arch Clin Neuropsychol Asunto de la revista: NEUROLOGIA / PSICOLOGIA Año: 2020 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Estados Unidos

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Trastornos por Estrés Postraumático / Veteranos / Lesiones Traumáticas del Encéfalo Tipo de estudio: Diagnostic_studies / Observational_studies / Prevalence_studies / Risk_factors_studies Límite: Humans Idioma: En Revista: Arch Clin Neuropsychol Asunto de la revista: NEUROLOGIA / PSICOLOGIA Año: 2020 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Estados Unidos