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Recent Progress of Stem Cell Therapy in Cancer Treatment: Molecular Mechanisms and Potential Applications.
Chu, Dinh-Toi; Nguyen, Tiep Tien; Tien, Nguyen Le Bao; Tran, Dang-Khoa; Jeong, Jee-Heon; Anh, Pham Gia; Thanh, Vo Van; Truong, Dang Tien; Dinh, Thien Chu.
Afiliación
  • Chu DT; Department of Human and Animal Physiology, Faculty of Biology, Hanoi National University of Education, Hanoi 100000, Vietnam.
  • Nguyen TT; College of Pharmacy, Yeungnam University, 280 Daehak-ro, Gyeongsan-si, Gyeongbuk-do 38541, Korea.
  • Tien NLB; Institute of Orthopaedics and Trauma Surgery, Viet Duc Hospital, Hanoi 100000, Vietnam.
  • Tran DK; Department of Anatomy, University of Medicine Pham Ngoc Thach, Ho Chi Minh City 700000, Vietnam.
  • Jeong JH; College of Pharmacy, Yeungnam University, 280 Daehak-ro, Gyeongsan-si, Gyeongbuk-do 38541, Korea.
  • Anh PG; Oncology Department, Viet Duc Hospital, Hanoi 100000, Vietnam.
  • Thanh VV; Institute of Orthopaedics and Trauma Surgery, Viet Duc Hospital, Hanoi 100000, Vietnam.
  • Truong DT; Department of Surgery, Hanoi Medical University, Hanoi 100000, Vietnam.
  • Dinh TC; Department of Anatomy, Vietnam Military Medical University, Hanoi 100000, Vietnam.
Cells ; 9(3)2020 02 28.
Article en En | MEDLINE | ID: mdl-32121074
The insufficient and unspecific target of traditional therapeutic approaches in cancer treatment often leads to therapy resistance and cancer recurrence. Over the past decades, accumulating discoveries about stem cell biology have provided new potential approaches to cure cancer patients. Stem cells possess unique biological actions, including self-renewal, directional migration, differentiation, and modulatory effects on other cells, which can be utilized as regenerative medicine, therapeutic carriers, drug targeting, and generation of immune cells. In this review, we emphasize the mechanisms underlying the use of various types of stem cells in cancer treatment. In addition, we summarize recent progress in the clinical applications of stem cells, as well as common risks of this therapy. We finally give general directions for future studies, aiming to improve overall outcomes in the fight against cancer.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Trasplante de Células Madre / Neoplasias Tipo de estudio: Etiology_studies / Risk_factors_studies Límite: Humans Idioma: En Revista: Cells Año: 2020 Tipo del documento: Article País de afiliación: Vietnam Pais de publicación: Suiza
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Trasplante de Células Madre / Neoplasias Tipo de estudio: Etiology_studies / Risk_factors_studies Límite: Humans Idioma: En Revista: Cells Año: 2020 Tipo del documento: Article País de afiliación: Vietnam Pais de publicación: Suiza