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Long-term swallowing, trismus, and speech outcomes after combined chemoradiotherapy and preventive rehabilitation for head and neck cancer; 10-year plus update.
Karsten, Rebecca T; van der Molen, Lisette; Hamming-Vrieze, Olga; van Son, Rob J J H; Hilgers, Frans J M; van den Brekel, Michiel W M; Stuiver, Martijn M; Smeele, Ludi E.
Afiliación
  • Karsten RT; Department of Head and Neck Oncology and Surgery, The Netherlands Cancer Institute, Amsterdam, The Netherlands.
  • van der Molen L; Department of Head and Neck Oncology and Surgery, The Netherlands Cancer Institute, Amsterdam, The Netherlands.
  • Hamming-Vrieze O; Department of Linguistics, Amsterdam Center for Language and Communication/ACLC-Institute of Phonetic Sciences, University of Amsterdam, Amsterdam, The Netherlands.
  • van Son RJJH; Department of Radiation Oncology, The Netherlands Cancer Institute, Amsterdam, The Netherlands.
  • Hilgers FJM; Department of Head and Neck Oncology and Surgery, The Netherlands Cancer Institute, Amsterdam, The Netherlands.
  • van den Brekel MWM; Department of Linguistics, Amsterdam Center for Language and Communication/ACLC-Institute of Phonetic Sciences, University of Amsterdam, Amsterdam, The Netherlands.
  • Stuiver MM; Department of Head and Neck Oncology and Surgery, The Netherlands Cancer Institute, Amsterdam, The Netherlands.
  • Smeele LE; Department of Linguistics, Amsterdam Center for Language and Communication/ACLC-Institute of Phonetic Sciences, University of Amsterdam, Amsterdam, The Netherlands.
Head Neck ; 42(8): 1907-1918, 2020 08.
Article en En | MEDLINE | ID: mdl-32112600
BACKGROUND: The objective of this study was to explore the 10-year plus outcomes of Intensity Modulated Radiotherapy with concomitant chemotherapy (CRT) combined with preventive swallowing rehabilitation (CRT+) for head and neck cancer (HNC). METHODS: Subjective and objective swallowing, trismus, and speech related outcomes were assessed at 10-year plus after CRT+. Outcomes were compared to previously published 6-year results of the same cohort. RESULTS: Fourteen of the 22 patients at 6-year follow-up were evaluable. Although objective swallowing-related outcomes showed no deterioration (eg, no feeding tube dependency and no pneumonia), swallowing-related quality of life slightly deteriorated over time. No patients had or perceived trismus. Voice and speech questionnaires showed little problems in daily life. Overall quality of life (QOL) was good. CONCLUSIONS: After CRT with preventive rehabilitation exercises for advanced HNC, swallowing, trismus, and speech related outcomes moderately deteriorated from 6 to 10 years, with an on average good overall QOL after.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Trastornos de Deglución / Neoplasias de Cabeza y Cuello Tipo de estudio: Etiology_studies Aspecto: Patient_preference Límite: Humans Idioma: En Revista: Head Neck Asunto de la revista: NEOPLASIAS Año: 2020 Tipo del documento: Article País de afiliación: Países Bajos Pais de publicación: Estados Unidos
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Trastornos de Deglución / Neoplasias de Cabeza y Cuello Tipo de estudio: Etiology_studies Aspecto: Patient_preference Límite: Humans Idioma: En Revista: Head Neck Asunto de la revista: NEOPLASIAS Año: 2020 Tipo del documento: Article País de afiliación: Países Bajos Pais de publicación: Estados Unidos