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Sodium-hydrogen exchanger 6 (NHE6) deficiency leads to hearing loss, via reduced endosomal signalling through the BDNF/Trk pathway.
Kucharava, Krystsina; Brand, Yves; Albano, Giuseppe; Sekulic-Jablanovic, Marijana; Glutz, Andrea; Xian, Xunde; Herz, Joachim; Bodmer, Daniel; Fuster, Daniel G; Petkovic, Vesna.
Afiliación
  • Kucharava K; Department of Biomedicine, and Clinic for Otolaryngology, Head and Neck Surgery, Hospital Basel, University of Basel, Basel, 4031, Switzerland.
  • Brand Y; Clinic for Otolaryngology, Head and Neck Surgery, Kantonsspital Graubünden, Chur, 7000, Switzerland.
  • Albano G; Department of Nephrology and Hypertension, Inselspital, Bern University Hospital, and NCCR Transcure, University of Bern, Bern, Switzerland.
  • Sekulic-Jablanovic M; Department of Biomedicine, and Clinic for Otolaryngology, Head and Neck Surgery, Hospital Basel, University of Basel, Basel, 4031, Switzerland.
  • Glutz A; Department of Biomedicine, and Clinic for Otolaryngology, Head and Neck Surgery, Hospital Basel, University of Basel, Basel, 4031, Switzerland.
  • Xian X; Center for Translational Neurodegeneration Research, University of Texas Southwestern Medical Center, Dallas, TX, 75390, USA.
  • Herz J; Department of Molecular Genetics, University of Texas Southwestern Medical Center, Dallas, TX, 75390, USA.
  • Bodmer D; Center for Translational Neurodegeneration Research, University of Texas Southwestern Medical Center, Dallas, TX, 75390, USA.
  • Fuster DG; Department of Molecular Genetics, University of Texas Southwestern Medical Center, Dallas, TX, 75390, USA.
  • Petkovic V; Department of Biomedicine, and Clinic for Otolaryngology, Head and Neck Surgery, Hospital Basel, University of Basel, Basel, 4031, Switzerland.
Sci Rep ; 10(1): 3609, 2020 02 27.
Article en En | MEDLINE | ID: mdl-32107410
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Órgano Espiral / Endosomas / Ganglio Espiral de la Cóclea / Intercambiadores de Sodio-Hidrógeno / Pérdida Auditiva / Neuronas Límite: Animals Idioma: En Revista: Sci Rep Año: 2020 Tipo del documento: Article País de afiliación: Suiza Pais de publicación: Reino Unido
Texto completo
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XML
PubMed Links
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Órgano Espiral / Endosomas / Ganglio Espiral de la Cóclea / Intercambiadores de Sodio-Hidrógeno / Pérdida Auditiva / Neuronas Límite: Animals Idioma: En Revista: Sci Rep Año: 2020 Tipo del documento: Article País de afiliación: Suiza Pais de publicación: Reino Unido