Myeloid-derived suppressor cells impede T cell functionality and promote Th17 differentiation in oral squamous cell carcinoma.

Dar, Asif A; Patil, Rushikesh S; Pradhan, Trupti N; Chaukar, Devendra A; D'Cruz, Anil K; Chiplunkar, Shubhada V

Dar, Asif A; Patil, Rushikesh S; Pradhan, Trupti N; Chaukar, Devendra A; D'Cruz, Anil K; Chiplunkar, Shubhada V.

Afiliación

Dar AA; Chiplunkar Lab, Advanced Centre for Treatment, Research and Education in Cancer (ACTREC), Tata Memorial Centre, Kharghar, Navi Mumbai, Maharashtra, 410210, India.
Patil RS; Homi Bhabha National Institute, Anushaktinagar, Mumbai, Maharashtra, 400094, India.
Pradhan TN; Chiplunkar Lab, Advanced Centre for Treatment, Research and Education in Cancer (ACTREC), Tata Memorial Centre, Kharghar, Navi Mumbai, Maharashtra, 410210, India.
Chaukar DA; Homi Bhabha National Institute, Anushaktinagar, Mumbai, Maharashtra, 400094, India.
D'Cruz AK; Chiplunkar Lab, Advanced Centre for Treatment, Research and Education in Cancer (ACTREC), Tata Memorial Centre, Kharghar, Navi Mumbai, Maharashtra, 410210, India.
Chiplunkar SV; Tata Memorial Hospital, Tata Memorial Centre, Dr. E. Borges Road, Parel, Mumbai, Maharashtra, 400012, India.

Cancer Immunol Immunother ; 69(6): 1071-1086, 2020 Jun.

Article en En | MEDLINE | ID: mdl-32103293

Asunto(s)

Carcinoma de Células Escamosas/genética; Neoplasias de la Boca/genética; Células Supresoras de Origen Mieloide/inmunología; Células Th17/inmunología; Diferenciación Celular; Femenino; Humanos; Masculino; Persona de Mediana Edad

Palabras clave

Myeloid-derived suppressor cells; Oral cancer; STAT3; T regulatory cells; TCR CD3-Î¶ chain; Th17 cells

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Neoplasias de la Boca / Carcinoma de Células Escamosas / Células Th17 / Células Supresoras de Origen Mieloide Límite: Female / Humans / Male / Middle aged Idioma: En Revista: Cancer Immunol Immunother Asunto de la revista: ALERGIA E IMUNOLOGIA / NEOPLASIAS / TERAPEUTICA Año: 2020 Tipo del documento: Article País de afiliación: India Pais de publicación: Alemania

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