Synthesis, Cytotoxic and Heparanase Inhibition Studies of 5-oxo-1-arylpyrrolidine-3- carboxamides of Hydrazides and 4-amino-5-aryl-4H-1,2,4-triazole-3-thiol.

Hari, Swetha; Swaroop, Toreshettahally R; Preetham, Habbanakuppe D; Mohan, Chakrabhavi D; Muddegowda, Umashakara; Basappa, Salundi; Vlodavsky, Israel; Sethi, Gautam; Rangappa, Kanchugarakoppal S

Hari, Swetha; Swaroop, Toreshettahally R; Preetham, Habbanakuppe D; Mohan, Chakrabhavi D; Muddegowda, Umashakara; Basappa, Salundi; Vlodavsky, Israel; Sethi, Gautam; Rangappa, Kanchugarakoppal S.

Afiliación

Hari S; Department of Studies in Chemistry, University of Mysore, Manasagangotri, Mysuru-570006, Karnataka, India.
Swaroop TR; Department of Studies in Organic Chemistry, University of Mysore, Manasagangotri, Mysuru-570006, Karnataka, India.
Preetham HD; Department of Studies in Chemistry, University of Mysore, Manasagangotri, Mysuru-570006, Karnataka, India.
Mohan CD; Department of Studies in Molecular Biology, University of Mysore, Manasagangotri, Mysuru-570006, Karnataka, India.
Muddegowda U; Department of Studies in Chemistry, Karnataka State Open University, Mukthagangothri, Mysuru-570006, Karnataka, India.
Basappa S; Department of Studies in Organic Chemistry, University of Mysore, Manasagangotri, Mysuru-570006, Karnataka, India.
Vlodavsky I; Cancer and Vascular Biology Research Center, the Bruce, Rappaport Faculty of Medicine, Technion, Haifa, Israel.
Sethi G; Department of Pharmacology, Yong Loo Lin School of Medicine, National University of Singapore, 117600, Singapore.
Rangappa KS; Department of Studies in Chemistry, University of Mysore, Manasagangotri, Mysuru-570006, Karnataka, India.

Curr Org Synth ; 17(3): 243-250, 2020.

Article en En | MEDLINE | ID: mdl-32096746

Asunto(s)

Antineoplásicos/farmacología; Inhibidores Enzimáticos/farmacología; Glucuronidasa/antagonistas & inhibidores; Hidrazinas/farmacología; Pirrolidinonas/farmacología; Triazoles/farmacología; Animales; Antineoplásicos/síntesis química; Línea Celular Tumoral; Inhibidores Enzimáticos/síntesis química; Humanos; Hidrazinas/síntesis química; Ratones; Pirrolidinonas/síntesis química; Triazoles/síntesis química

Palabras clave

Hydrazides; carboxamides; cytotoxicity; heparanase; pyrrolidine; triazole.

Texto completo

Añadir a Mi BVS

Imprimir

XML

PubMed Links

Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Pirrolidinonas / Triazoles / Inhibidores Enzimáticos / Glucuronidasa / Hidrazinas / Antineoplásicos Límite: Animals / Humans Idioma: En Revista: Curr Org Synth Año: 2020 Tipo del documento: Article País de afiliación: India Pais de publicación: Emiratos Árabes Unidos

Texto completo

Añadir a Mi BVS

Imprimir

XML

PubMed Links

Buscar en Google