Your browser doesn't support javascript.
loading
Assessment of out-of-field doses in radiotherapy treatments of paediatric patients using Monte Carlo methods and measurements.
Cravo Sá, Ana; Barateiro, Andreia; Bednarz, Bryan; Borges, Cecília; Pereira, Joana; Baptista, Mariana; Pereira, Miguel; Zarza-Moreno, Miriam; Almeida, Pedro; Vaz, Pedro; Madaleno, Tiago; Romanets, Yuriy.
Afiliación
  • Cravo Sá A; Centro de Ciências e Tecnologias Nucleares, Instituto Superior Técnico, Campus Tecnológico e Nuclear, Estrada Nacional 10, km 139,7, 2695-066 Bobadela LRS, Portugal; Universidade de Lisboa, Faculdade de Ciências, Instituto de Biofísica e Engenharia Biomédica, Campo Grande, Lisboa 1749-016, Portugal;
  • Barateiro A; Serviço de Radioterapia, Instituto Português de Oncologia de Lisboa Francisco Gentil, R. Prof° Lima Basto, 1099-023 Lisboa, Portugal.
  • Bednarz B; Department of Medical Physics, Wisconsin Institutes for Medical Research, University of Wisconsin-Madison, 1111 Highland Ave., L5-176, Madison, WI 53705-2275, USA.
  • Borges C; Mediclinic City Hospital FZ L.L.C., PO Box 505004, Building 35&37, Dubai Healthcare City, Dubai, United Arab Emirates.
  • Pereira J; Centro de Ciências e Tecnologias Nucleares, Instituto Superior Técnico, Campus Tecnológico e Nuclear, Estrada Nacional 10, km 139,7, 2695-066 Bobadela LRS, Portugal; Laboratório de Proteção e Segurança Radiológica, Instituto Superior Técnico, Campus Tecnológico e Nuclear, Estrada Nacional 10, km 139
  • Baptista M; Centro de Ciências e Tecnologias Nucleares, Instituto Superior Técnico, Campus Tecnológico e Nuclear, Estrada Nacional 10, km 139,7, 2695-066 Bobadela LRS, Portugal.
  • Pereira M; Centro de Ciências e Tecnologias Nucleares, Instituto Superior Técnico, Campus Tecnológico e Nuclear, Estrada Nacional 10, km 139,7, 2695-066 Bobadela LRS, Portugal; Laboratório de Proteção e Segurança Radiológica, Instituto Superior Técnico, Campus Tecnológico e Nuclear, Estrada Nacional 10, km 139
  • Zarza-Moreno M; Serviço de Radioterapia, Instituto Português de Oncologia de Lisboa Francisco Gentil, R. Prof° Lima Basto, 1099-023 Lisboa, Portugal.
  • Almeida P; Universidade de Lisboa, Faculdade de Ciências, Instituto de Biofísica e Engenharia Biomédica, Campo Grande, Lisboa 1749-016, Portugal.
  • Vaz P; Centro de Ciências e Tecnologias Nucleares, Instituto Superior Técnico, Campus Tecnológico e Nuclear, Estrada Nacional 10, km 139,7, 2695-066 Bobadela LRS, Portugal.
  • Madaleno T; Serviço de Radioterapia, Instituto Português de Oncologia de Lisboa Francisco Gentil, R. Prof° Lima Basto, 1099-023 Lisboa, Portugal.
  • Romanets Y; Centro de Ciências e Tecnologias Nucleares, Instituto Superior Técnico, Campus Tecnológico e Nuclear, Estrada Nacional 10, km 139,7, 2695-066 Bobadela LRS, Portugal.
Phys Med ; 71: 53-61, 2020 Mar.
Article en En | MEDLINE | ID: mdl-32088565
PURPOSE: To assess out-of-field doses in radiotherapy treatments of paediatric patients, using Monte Carlo methods to implement a new model of the linear accelerator validated against measurements and developing a voxelized anthropomorphic paediatric phantom. METHODS: CT images of a physical anthropomorphic paediatric phantom were acquired and a dosimetric planning using a TPS was obtained. The CT images were used to perform the voxelization of the physical phantom using the ImageJ software and later implemented in MCNP. In order to validate the Monte Carlo model, dose measurements of the 6 MV beam and Linac with 120 MLC were made in a clinical setting, using ionization chambers and a water phantom. Afterwards TLD measurements in the physical anthropomorphic phantom were performed in order to assess the out-of-field doses in the eyes, thyroid, c-spine, heart and lungs. RESULTS: The Monte Carlo model was validated for in-field and out-of-field doses with average relative differences below 3%. The average relative differences between TLD measurements and Monte Carlo is 14,3% whilst the average relative differences between TLD and TPS is 55,8%. Moreover, organs up to 22.5 cm from PTV center show TLD and MCNP6 relative differences and TLD and TPS relative differences up to 21.2% and 92.0%, respectively. CONCLUSIONS: Our study provides a novel model that could be used in clinical research, namely in dose evaluation outside the treatment fields. This is particularly relevant, especially in pediatric patients, for studying new radiotherapy treatment techniques, since it can be used to estimate the development of secondary tumours.
Asunto(s)
Palabras clave
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Aceleradores de Partículas / Radioterapia / Dosimetría Termoluminiscente / Planificación de la Radioterapia Asistida por Computador / Método de Montecarlo / Neoplasias Tipo de estudio: Health_economic_evaluation Límite: Child, preschool / Humans Idioma: En Revista: Phys Med Asunto de la revista: BIOFISICA / BIOLOGIA / MEDICINA Año: 2020 Tipo del documento: Article Pais de publicación: Italia
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Aceleradores de Partículas / Radioterapia / Dosimetría Termoluminiscente / Planificación de la Radioterapia Asistida por Computador / Método de Montecarlo / Neoplasias Tipo de estudio: Health_economic_evaluation Límite: Child, preschool / Humans Idioma: En Revista: Phys Med Asunto de la revista: BIOFISICA / BIOLOGIA / MEDICINA Año: 2020 Tipo del documento: Article Pais de publicación: Italia