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Oncological and functional outcomes after repeat transoral laser microsurgery for the treatment of recurrent early glottic cancer.
Forner, D; Rigby, M H; Corsten, M; Trites, J R; Pyne, J; Taylor, S M.
Afiliación
  • Forner D; Division of Otolaryngology - Head and Neck Surgery, Department of Surgery, Dalhousie University, Halifax, Canada.
  • Rigby MH; Division of Otolaryngology - Head and Neck Surgery, Department of Surgery, Dalhousie University, Halifax, Canada.
  • Corsten M; Division of Otolaryngology - Head and Neck Surgery, Department of Surgery, Dalhousie University, Halifax, Canada.
  • Trites JR; Division of Otolaryngology - Head and Neck Surgery, Department of Surgery, Dalhousie University, Halifax, Canada.
  • Pyne J; Division of Otolaryngology - Head and Neck Surgery, Department of Surgery, University of Alberta, Edmonton, Canada.
  • Taylor SM; Division of Otolaryngology - Head and Neck Surgery, Department of Surgery, Dalhousie University, Halifax, Canada.
J Laryngol Otol ; : 1-5, 2020 Feb 21.
Article en En | MEDLINE | ID: mdl-32079549
BACKGROUND: Transoral laser microsurgery for glottic squamous cell carcinoma is the standard of care at many institutions. Repeat transoral laser microsurgery for recurrence may avoid the need for radiotherapy and total laryngectomy. This study aimed to identify oncological and functional outcomes in a cohort of patients who had undergone repeat transoral laser microsurgery procedures. METHOD: A retrospective review of prospectively collected data of patients treated with transoral laser microsurgery for carcinoma in situ or tumour stages T1 or T2 glottic cancer, from 2003 to 2018. RESULTS: Twenty patients were identified. Additional treatment was not needed in 45 per cent of patients. The five-year overall survival rate was 90 per cent. The disease-specific survival rate was 100 per cent. The laryngeal preservation rate was 85 per cent. There was improvement in mean Voice Handicap Index-10 scores following repeat transoral laser microsurgery treatment, when comparing the pre- and post-operative periods (mean scores = 15.5 vs 11.5, p = 0.373). CONCLUSION: Repeat transoral laser microsurgery can be an oncologically safe alternative to other salvage therapies for glottic squamous cell carcinoma recurrence, without sacrificing functional outcomes.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Tipo de estudio: Prognostic_studies Idioma: En Revista: J Laryngol Otol Asunto de la revista: OTORRINOLARINGOLOGIA Año: 2020 Tipo del documento: Article País de afiliación: Canadá Pais de publicación: Reino Unido

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Tipo de estudio: Prognostic_studies Idioma: En Revista: J Laryngol Otol Asunto de la revista: OTORRINOLARINGOLOGIA Año: 2020 Tipo del documento: Article País de afiliación: Canadá Pais de publicación: Reino Unido