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Lipid droplet-mediated scavenging as novel intrinsic and adaptive resistance factor against the multikinase inhibitor ponatinib.
Englinger, Bernhard; Laemmerer, Anna; Moser, Patrick; Kallus, Sebastian; Röhrl, Clemens; Pirker, Christine; Baier, Dina; Mohr, Thomas; Niederstaetter, Laura; Meier-Menches, Samuel M; Gerner, Christopher; Gabler, Lisa; Gojo, Johannes; Timelthaler, Gerald; Senkiv, Julia; Jäger, Walter; Kowol, Christian R; Heffeter, Petra; Berger, Walter.
Afiliación
  • Englinger B; Department of Medicine I, Medical University of Vienna, Institute of Cancer Research and Comprehensive Cancer Center, Vienna, Austria.
  • Laemmerer A; Research Cluster "Translational Cancer Therapy Research", University of Vienna, Vienna, Austria.
  • Moser P; Department of Medicine I, Medical University of Vienna, Institute of Cancer Research and Comprehensive Cancer Center, Vienna, Austria.
  • Kallus S; Research Cluster "Translational Cancer Therapy Research", University of Vienna, Vienna, Austria.
  • Röhrl C; Department of Medicine I, Medical University of Vienna, Institute of Cancer Research and Comprehensive Cancer Center, Vienna, Austria.
  • Pirker C; Research Cluster "Translational Cancer Therapy Research", University of Vienna, Vienna, Austria.
  • Baier D; Institute of Inorganic Chemistry, Faculty of Chemistry, University of Vienna, Vienna, Austria.
  • Mohr T; Center for Pathobiochemistry and Genetics, Medical University of Vienna, Vienna, Austria.
  • Niederstaetter L; University of Applied Sciences Upper Austria, Wels, Austria.
  • Meier-Menches SM; Department of Medicine I, Medical University of Vienna, Institute of Cancer Research and Comprehensive Cancer Center, Vienna, Austria.
  • Gerner C; Research Cluster "Translational Cancer Therapy Research", University of Vienna, Vienna, Austria.
  • Gabler L; Department of Medicine I, Medical University of Vienna, Institute of Cancer Research and Comprehensive Cancer Center, Vienna, Austria.
  • Gojo J; Research Cluster "Translational Cancer Therapy Research", University of Vienna, Vienna, Austria.
  • Timelthaler G; Institute of Inorganic Chemistry, Faculty of Chemistry, University of Vienna, Vienna, Austria.
  • Senkiv J; Department of Medicine I, Medical University of Vienna, Institute of Cancer Research and Comprehensive Cancer Center, Vienna, Austria.
  • Jäger W; Department of Analytical Chemistry, Faculty of Chemistry, University of Vienna, Vienna, Austria.
  • Kowol CR; Department of Analytical Chemistry, Faculty of Chemistry, University of Vienna, Vienna, Austria.
  • Heffeter P; Department of Analytical Chemistry, Faculty of Chemistry, University of Vienna, Vienna, Austria.
  • Berger W; Department of Medicine I, Medical University of Vienna, Institute of Cancer Research and Comprehensive Cancer Center, Vienna, Austria.
Int J Cancer ; 147(6): 1680-1693, 2020 09 15.
Article en En | MEDLINE | ID: mdl-32064608
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Piridazinas / Resistencia a Antineoplásicos / Inhibidores de Proteínas Quinasas / Gotas Lipídicas / Imidazoles / Neoplasias Pulmonares Tipo de estudio: Prognostic_studies Límite: Animals / Humans Idioma: En Revista: Int J Cancer Año: 2020 Tipo del documento: Article País de afiliación: Austria Pais de publicación: Estados Unidos
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Piridazinas / Resistencia a Antineoplásicos / Inhibidores de Proteínas Quinasas / Gotas Lipídicas / Imidazoles / Neoplasias Pulmonares Tipo de estudio: Prognostic_studies Límite: Animals / Humans Idioma: En Revista: Int J Cancer Año: 2020 Tipo del documento: Article País de afiliación: Austria Pais de publicación: Estados Unidos