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[Exposure to famine in fetus and infant period and risk for hypertension in adulthood].
You, Y Y; Song, Y; Wang, M H; Zhang, L L; Bai, W; Yu, W Y; Yu, Y Q; Kou, C G.
Afiliación
  • You YY; Department of Epidemiology and Statistics, School of Public Health, Jilin University, Changchun 130021, China; Health Education Division, Center for Chronic Disease Control, Nanshan District, Shenzhen 518000, China.
  • Song Y; Department of Epidemiology and Statistics, School of Public Health, Jilin University, Changchun 130021, China.
  • Wang MH; Department of Epidemiology and Statistics, School of Public Health, Jilin University, Changchun 130021, China.
  • Zhang LL; Department of Epidemiology and Statistics, School of Public Health, Jilin University, Changchun 130021, China.
  • Bai W; Department of Epidemiology and Statistics, School of Public Health, Jilin University, Changchun 130021, China.
  • Yu WY; Department of Epidemiology and Statistics, School of Public Health, Jilin University, Changchun 130021, China.
  • Yu YQ; Department of Epidemiology and Statistics, School of Public Health, Jilin University, Changchun 130021, China.
  • Kou CG; Department of Epidemiology and Statistics, School of Public Health, Jilin University, Changchun 130021, China.
Zhonghua Liu Xing Bing Xue Za Zhi ; 41(1): 74-78, 2020 Jan 10.
Article en Zh | MEDLINE | ID: mdl-32062946
Objective: To investigate the relationship between exposure to famine in fetus and infant period and the risks for hypertension in adulthood. Methods: A total of 5 960 participants born between 1956 and 1965 were included in the study and were divided into unexposed group (1963-1965), fetal exposed group (1959-1961), early- childhood exposed group (1956-1958) and transitional group (1962). Logistic regression model was used to explore the association between famine exposure in early life and the risk for hypertension in adulthood. Results: Both the fetal exposure and the early-childhood exposure were the risk factors for hypertension in adulthood (OR=1.249, 95%CI: 1.049-1.486 and OR=1.360, 95%CI: 1.102-1.679). Meanwhile, in rural area, compared with unexposed group, the fetal exposure (OR=1.401, 95%CI: 1.091-1.798) and the early-childhood exposure (OR=1.460, 95%CI: 1.145-1.862) were also associated with a greater risk of hypertension in adulthood. In addition, fetal exposure and early-childhood exposure to famine in women were associated with 36.0% and 31.9% increased risks for hypertension (95%CI: 7.8%-71.7% and 95%CI: 4.8%-66.0%) according to the stratified analysis. Conclusion: Fetal exposure to famine might increase the risk for hypertension in adulthood.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Efectos Tardíos de la Exposición Prenatal / Inanición / Hipertensión Tipo de estudio: Etiology_studies / Prognostic_studies / Risk_factors_studies Límite: Adult / Child / Female / Humans / Infant / Pregnancy País/Región como asunto: Asia Idioma: Zh Revista: Zhonghua Liu Xing Bing Xue Za Zhi Año: 2020 Tipo del documento: Article País de afiliación: China Pais de publicación: China
Texto completo
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Imprimir
XML
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Efectos Tardíos de la Exposición Prenatal / Inanición / Hipertensión Tipo de estudio: Etiology_studies / Prognostic_studies / Risk_factors_studies Límite: Adult / Child / Female / Humans / Infant / Pregnancy País/Región como asunto: Asia Idioma: Zh Revista: Zhonghua Liu Xing Bing Xue Za Zhi Año: 2020 Tipo del documento: Article País de afiliación: China Pais de publicación: China