Ohmic heating polyphenolic extracts from vine pruning residue with enhanced biological activity.

Jesus, Meirielly S; Ballesteros, Lina F; Pereira, Ricardo N; Genisheva, Zlatina; Carvalho, Ana C; Pereira-Wilson, Cristina; Teixeira, José A; Domingues, Lucília

Jesus, Meirielly S; Ballesteros, Lina F; Pereira, Ricardo N; Genisheva, Zlatina; Carvalho, Ana C; Pereira-Wilson, Cristina; Teixeira, José A; Domingues, Lucília.

Afiliación

Jesus MS; CEB - Centre of Biological Engineering, University of Minho, 4710-057 Braga, Portugal. Electronic address: merielly_@hotmail.com.
Ballesteros LF; CEB - Centre of Biological Engineering, University of Minho, 4710-057 Braga, Portugal. Electronic address: linafernanda37@gmail.com.
Pereira RN; CEB - Centre of Biological Engineering, University of Minho, 4710-057 Braga, Portugal. Electronic address: rpereira@deb.uminho.pt.
Genisheva Z; CEB - Centre of Biological Engineering, University of Minho, 4710-057 Braga, Portugal. Electronic address: zgenisheva@gmail.com.
Carvalho AC; Department of Biology, University of Minho, Braga, Portugal; Centre for the Research and Technology of Agro-Environmental and Biological Sciences, University of Tras-os-Montes e Alto Douro, Vila Real, Portugal. Electronic address: anacpcarvalho@gmail.com.
Pereira-Wilson C; CEB - Centre of Biological Engineering, University of Minho, 4710-057 Braga, Portugal; Department of Biology, University of Minho, Braga, Portugal. Electronic address: cpereira.bio.uminho@gmail.com.
Teixeira JA; CEB - Centre of Biological Engineering, University of Minho, 4710-057 Braga, Portugal. Electronic address: jateixeira@deb.uminho.pt.
Domingues L; CEB - Centre of Biological Engineering, University of Minho, 4710-057 Braga, Portugal. Electronic address: luciliad@deb.uminho.pt.

Food Chem ; 316: 126298, 2020 Jun 30.

Article en En | MEDLINE | ID: mdl-32062230

RESUMEN

Vine Pruning residue was submitted to conventional heating and ohmic heating (OH) for the extraction of bioactive compounds and analyzed for total phenolic content (TPC), polyphenolic profile, antioxidant activity, antimicrobial activity and anticancer activity. The OH extracts were obtained using Low electric field (496.0 V/cm) or Intermediate electric field - IEF (840.0 V/cm). The tests were performed using 45% (v/v) ethanol-water extraction solution at 80 °C at different extraction times (20-90 min). The extract that stood out among the others concerning anticancer potential was the one obtained by OH when used, IEF, where the TPC was significantly higher than in the other extracts which correlated with higher antioxidant, antimicrobial and anti-proliferative activity on different tumor cell lines (HepG2, MDA-MB-231, MCF-7 and Caco2). Vine pruning OH extracts obtained using green solvents by an eco-friendly procedure were revealed as a source of compounds with relevant antioxidant and anticancer activity.

Asunto(s)

Antioxidantes/química; Extractos Vegetales/química; Polifenoles/química; Vitis/química; Antioxidantes/farmacología; Línea Celular Tumoral; Proliferación Celular/efectos de los fármacos; Calor; Humanos; Polifenoles/farmacología

Palabras clave

ABTS (PubChem CID: 90658258); Anticancer activity; Antimicrobial activity; Antioxidant activity; Apigenin (PubChem CID: 5280443); Catechin (PubChem CID: 73160); DMSO (PubChem CID: 329830510); DPPH (PubChem CID: 2735032); Ellagic acid (PubChem CID: 5281855); Ferulic acid (PubChem CID: 445858); Gallic acid (PubChem CID: 370); Hesperidin (PubChem CID: 24895680); HidroxiTyrosol (PubChem CID: 329815209); Iron(II) sulfate (PubChem CID: 24393); Iron(III) Cloride (PubChem CID: 24380); MTT (PubChem CID: 24896603); Ohmic extraction; Phenolic compounds; Quercetin (PubChem CID: 5280343); Resveratrol (PubChem CID: 445154); Rosmarinic acid (PubChem CID: 5281792); TPTZ (PubChem CID: 77258); Taxifolin (PubChem CID: 329768169); Trolox (PubChem CID: 40634); Tyrosol (PubChem CID: 329768224); Vanillic acid (PubChem CID: 8468); Vine pruning residue; o-cumaric acid (PubChem CID: 637540)

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Extractos Vegetales / Vitis / Polifenoles / Antioxidantes Límite: Humans Idioma: En Revista: Food Chem Año: 2020 Tipo del documento: Article Pais de publicación: Reino Unido

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