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Thrombin/PAR-1 activation induces endothelial damages via NLRP1 inflammasome in gestational diabetes.
Liu, Yue; Tang, Zhuang-Zhuang; Zhang, Yu-Meng; Kong, Li; Xiao, Wei-Fen; Ma, Teng-Fei; Liu, Yao-Wu.
Afiliación
  • Liu Y; Jiangsu Key Laboratory of New Drug Research and Clinical Pharmacy, Xuzhou Medical University, Xuzhou 221004, Jiangsu, China.
  • Tang ZZ; Jiangsu Key Laboratory of New Drug Research and Clinical Pharmacy, Xuzhou Medical University, Xuzhou 221004, Jiangsu, China.
  • Zhang YM; Jiangsu Key Laboratory of New Drug Research and Clinical Pharmacy, Xuzhou Medical University, Xuzhou 221004, Jiangsu, China.
  • Kong L; Jiangsu Key Laboratory of New Drug Research and Clinical Pharmacy, Xuzhou Medical University, Xuzhou 221004, Jiangsu, China.
  • Xiao WF; Department of Obstetrics and Gynecology, Xuzhou Medical University Affiliated Hospital, Xuzhou 221006, Jiangsu, China.
  • Ma TF; Key Laboratory of Targeted Intervention of Cardiovascular Disease, Collaborative Innovation Center for Cardiovascular Disease Translational Medicine, Nanjing Medical University, Nanjing 211166, Jiangsu, China.
  • Liu YW; Jiangsu Key Laboratory of New Drug Research and Clinical Pharmacy, Xuzhou Medical University, Xuzhou 221004, Jiangsu, China; Department of Pharmacology, School of Pharmacy, Xuzhou Medical University, Xuzhou 221004, Jiangsu, China. Electronic address: ywliu@xzhmu.edu.cn.
Biochem Pharmacol ; 175: 113849, 2020 05.
Article en En | MEDLINE | ID: mdl-32059841
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Endotelio Vascular / Trombina / Diabetes Gestacional / Receptor PAR-1 / Proteínas Adaptadoras Transductoras de Señales / Proteínas Reguladoras de la Apoptosis / Inflamasomas Límite: Female / Humans / Pregnancy Idioma: En Revista: Biochem Pharmacol Año: 2020 Tipo del documento: Article País de afiliación: China Pais de publicación: Reino Unido
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Endotelio Vascular / Trombina / Diabetes Gestacional / Receptor PAR-1 / Proteínas Adaptadoras Transductoras de Señales / Proteínas Reguladoras de la Apoptosis / Inflamasomas Límite: Female / Humans / Pregnancy Idioma: En Revista: Biochem Pharmacol Año: 2020 Tipo del documento: Article País de afiliación: China Pais de publicación: Reino Unido