In vitro oxidative stress, mitochondrial impairment and G1 phase cell cycle arrest induced by alkyl-phosphorus-containing flame retardants.

Yuan, Shengwu; Zhu, Kongrui; Ma, Mei; Zhu, Xiaoshan; Rao, Kaifeng; Wang, Zijian

In vitro oxidative stress, mitochondrial impairment and G1 phase cell cycle arrest induced by alkyl-phosphorus-containing flame retardants.

Yuan, Shengwu; Zhu, Kongrui; Ma, Mei; Zhu, Xiaoshan; Rao, Kaifeng; Wang, Zijian.

Afiliación

Yuan S; Key Laboratory of Drinking Water Science and Technology, Research Center for Eco-Environmental Sciences, Chinese Academy of Sciences, Beijing, 100085, China; Graduate School at Shenzhen, Tsinghua University, Shenzhen, 518055, PR China.
Zhu K; Key Laboratory of Drinking Water Science and Technology, Research Center for Eco-Environmental Sciences, Chinese Academy of Sciences, Beijing, 100085, China; College of Resources and Environment, University of Chinese Academy of Sciences, Beijing, 100049, China.
Ma M; Key Laboratory of Drinking Water Science and Technology, Research Center for Eco-Environmental Sciences, Chinese Academy of Sciences, Beijing, 100085, China; College of Resources and Environment, University of Chinese Academy of Sciences, Beijing, 100049, China. Electronic address: mamei@rcees.ac.cn
Zhu X; Graduate School at Shenzhen, Tsinghua University, Shenzhen, 518055, PR China.
Rao K; Key Laboratory of Drinking Water Science and Technology, Research Center for Eco-Environmental Sciences, Chinese Academy of Sciences, Beijing, 100085, China.
Wang Z; State Key Laboratory of Environmental Aquatic Chemistry, Research Center for Eco-Environmental Sciences, Chinese Academy of Sciences, Beijing, 100085, China.

Chemosphere ; 248: 126026, 2020 Jun.

Article en En | MEDLINE | ID: mdl-32006839

Asunto(s)

Retardadores de Llama/toxicidad; Puntos de Control de la Fase G1 del Ciclo Celular/efectos de los fármacos; Estrés Oxidativo/efectos de los fármacos; Células A549; Daño del ADN; Contaminantes Ambientales/toxicidad; Humanos; Mitocondrias/efectos de los fármacos; Organofosfatos/toxicidad; Fósforo/química; Pruebas de Toxicidad; Factores de Transcripción/genética

Palabras clave

Cell apoptosis; DNA damage; Mitochondrial impairment; Oxidative stress; Phosphorus-containing flame retardants

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Estrés Oxidativo / Puntos de Control de la Fase G1 del Ciclo Celular / Retardadores de Llama Límite: Humans Idioma: En Revista: Chemosphere Año: 2020 Tipo del documento: Article Pais de publicación: Reino Unido

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