New insights of CYP1A in endogenous metabolism: a focus on single nucleotide polymorphisms and diseases.

Lu, Jian; Shang, Xuyang; Zhong, Weiguo; Xu, Yuan; Shi, Rong; Wang, Xin

Lu, Jian; Shang, Xuyang; Zhong, Weiguo; Xu, Yuan; Shi, Rong; Wang, Xin.

Afiliación

Lu J; Changning Maternity and Infant Health Hospital, East China Normal University, Shanghai 200051, China.
Shang X; Shanghai Key Laboratory of Regulatory Biology, Institute of Biomedical Sciences and School of Life Sciences, East China Normal University, Shanghai 200241, China.
Zhong W; Changning Maternity and Infant Health Hospital, East China Normal University, Shanghai 200051, China.
Xu Y; Shanghai Key Laboratory of Regulatory Biology, Institute of Biomedical Sciences and School of Life Sciences, East China Normal University, Shanghai 200241, China.
Shi R; Changning Maternity and Infant Health Hospital, East China Normal University, Shanghai 200051, China.
Wang X; Shanghai Key Laboratory of Regulatory Biology, Institute of Biomedical Sciences and School of Life Sciences, East China Normal University, Shanghai 200241, China.

Acta Pharm Sin B ; 10(1): 91-104, 2020 Jan.

Article en En | MEDLINE | ID: mdl-31998606

Palabras clave

CYP, cytochrome P450; CYP1A; EOAs, cis-epoxyoctadecenoics; Endogenous substances; FSH, follicle stimulating hormone; HODEs, hydroxyoctadecdienoic acids; IQ, 2-amino-3-methylimidazo [4,5-f] quinoline; KO, knockout; LIF/STAT3, inhibiting leukemia inhibitory factor/signal transducer and activator of transcription 3; Metabolism and disease; PhIP, 2-amino-1-methyl-6-phenylimidazo [4,5-b] pyridine; SNPs; SNPs, single nucleotide polymorphisms; WT, wild type; Xenobiotics; t-RA, all-trans-retinoic acid; t-ROH, all-trans-retinol

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Tipo de estudio: Prognostic_studies Idioma: En Revista: Acta Pharm Sin B Año: 2020 Tipo del documento: Article País de afiliación: China Pais de publicación: Países Bajos

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