Colchicine-like ß-acetamidoketones as inhibitors of microtubule polymerization: Design, synthesis and biological evaluation of <i>in vitro</i> anticancer activity.

Karimikia, Ehsan; Behravan, Javad; Zarghi, Afshin; Ghandadi, Morteza; Omid Malayeri, Sina; Ghodsi, Razieh

Colchicine-like ß-acetamidoketones as inhibitors of microtubule polymerization: Design, synthesis and biological evaluation of in vitro anticancer activity.

Karimikia, Ehsan; Behravan, Javad; Zarghi, Afshin; Ghandadi, Morteza; Omid Malayeri, Sina; Ghodsi, Razieh.

Afiliación

Karimikia E; Biotechnology Research Center, Pharmaceutical Technology Institute, Mashhad University of Medical Sciences, Mashhad, Iran.
Behravan J; Department of Medicinal Chemistry, School of Pharmacy, Mashhad University of Medical Sciences, Mashhad, Iran.
Zarghi A; Biotechnology Research Center, Pharmaceutical Technology Institute, Mashhad University of Medical Sciences, Mashhad, Iran.
Ghandadi M; Department of Pharmaceutical Chemistry, School of Pharmacy, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Omid Malayeri S; Department of Medicinal Chemistry, School of Pharmacy, Mashhad University of Medical Sciences, Mashhad, Iran.
Ghodsi R; Department of Medicinal Chemistry, School of Pharmacy, Mashhad University of Medical Sciences, Mashhad, Iran.

Iran J Basic Med Sci ; 22(10): 1138-1146, 2019 Oct.

Article en En | MEDLINE | ID: mdl-31998454

Palabras clave

Anticancer activity; Chalcone; Colchicine; Colchicinelike; Molecular docking; Tubulin polymerization; ß-acetamidoketones

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Iran J Basic Med Sci Año: 2019 Tipo del documento: Article País de afiliación: Irán Pais de publicación: Irán

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