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Co-circulation of multiple enterovirus D68 subclades, including a novel B3 cluster, across Europe in a season of expected low prevalence, 2019/20.
Midgley, Sofie Elisabeth; Benschop, Kimberley; Dyrdak, Robert; Mirand, Audrey; Bailly, Jean-Luc; Bierbaum, Sibylle; Buderus, Stefan; Böttcher, Sindy; Eis-Hübinger, Anna-Maria; Hönemann, Mario; Jensen, Veronika Vorobieva; Hartling, Ulla Birgitte; Henquell, Cécile; Panning, Marcus; Thomsen, Marianne Kragh; Hodcroft, Emma B; Meijer, Adam.
Afiliación
  • Midgley SE; Department for Virus and Microbiological Special Diagnostics, Statens Serum Institut, Copenhagen, Denmark.
  • Benschop K; Centre for Infectious Disease Research, Diagnostics and Laboratory Surveillance, National Institute for Public Health and the Environment (RIVM), Bilthoven, the Netherlands.
  • Dyrdak R; Department of Clinical Microbiology, Karolinska University Hospital, Stockholm, Sweden.
  • Mirand A; Department of Microbiology, Tumor and Cell Biology, Karolinska Institutet, Stockholm, Sweden.
  • Bailly JL; CHU Clermont-Ferrand, Centre National de Référence des entérovirus et parechovirus - Laboratoire Associé, Laboratoire de Virologie, Clermont-Ferrand, France.
  • Bierbaum S; Université Clermont Auvergne, CNRS, Laboratoire Microorganismes: Génome et Environnement, Clermont-Ferrand, France.
  • Buderus S; Université Clermont Auvergne, CNRS, Laboratoire Microorganismes: Génome et Environnement, Clermont-Ferrand, France.
  • Böttcher S; Institute of Virology, University of Freiburg, Freiburg, Germany.
  • Eis-Hübinger AM; Department of General Pediatrics, St.-Marien-Hospital, Bonn, Germany.
  • Hönemann M; National Reference Center for Poliomyelitis and Enteroviruses, Robert Koch-Institute, Berlin, Germany.
  • Jensen VV; Institute of Virology, University of Bonn Medical Center, Bonn, Germany.
  • Hartling UB; Institute of Virology, University of Leipzig, Leipzig, Germany.
  • Henquell C; Department for Virus and Microbiological Special Diagnostics, Statens Serum Institut, Copenhagen, Denmark.
  • Panning M; Department of Paediatrics, Aarhus University Hospital, Aarhus, Denmark.
  • Thomsen MK; CHU Clermont-Ferrand, Centre National de Référence des entérovirus et parechovirus - Laboratoire Associé, Laboratoire de Virologie, Clermont-Ferrand, France.
  • Hodcroft EB; Institute of Virology, University of Freiburg, Freiburg, Germany.
  • Meijer A; Department of Clinical Microbiology, Aarhus University Hospital, Aarhus, Denmark.
Euro Surveill ; 25(2)2020 01.
Article en En | MEDLINE | ID: mdl-31964463
Enterovirus D68 (EV-D68) was detected in 93 patients from five European countries between 1 January 2019 and 15 January 2020, a season with expected low circulation. Patients were primarily children (n = 67, median age: 4 years), 59 patients required hospitalisation and five had severe neurologic manifestations. Phylogenetic analysis revealed two clusters in the B3 subclade and subclade A2/D. This circulation of EV-D68 associated with neurological manifestations stresses the importance of surveillance and diagnostics beyond expected peak years.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Infecciones del Sistema Respiratorio / Brotes de Enfermedades / Enterovirus Humano D / Infecciones por Enterovirus / Enfermedades del Sistema Nervioso Tipo de estudio: Prevalence_studies / Risk_factors_studies / Screening_studies Límite: Adolescent / Adult / Aged / Aged80 / Child / Child, preschool / Female / Humans / Infant / Male País/Región como asunto: Europa Idioma: En Revista: Euro Surveill Asunto de la revista: DOENCAS TRANSMISSIVEIS Año: 2020 Tipo del documento: Article País de afiliación: Dinamarca Pais de publicación: Suecia
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Infecciones del Sistema Respiratorio / Brotes de Enfermedades / Enterovirus Humano D / Infecciones por Enterovirus / Enfermedades del Sistema Nervioso Tipo de estudio: Prevalence_studies / Risk_factors_studies / Screening_studies Límite: Adolescent / Adult / Aged / Aged80 / Child / Child, preschool / Female / Humans / Infant / Male País/Región como asunto: Europa Idioma: En Revista: Euro Surveill Asunto de la revista: DOENCAS TRANSMISSIVEIS Año: 2020 Tipo del documento: Article País de afiliación: Dinamarca Pais de publicación: Suecia