Your browser doesn't support javascript.
loading
A Robotic Biopsy Endoscope with Magnetic 5-DOF Locomotion and a Retractable Biopsy Punch.
Hoang, Manh Cuong; Le, Viet Ha; Nguyen, Kim Tien; Nguyen, Van Du; Kim, Jayoung; Choi, Eunpyo; Bang, Seungmin; Kang, Byungjeon; Park, Jong-Oh; Kim, Chang-Sei.
Afiliación
  • Hoang MC; Department of Mechanical Engineering, Chonnam National University, Gwangju 61186, Korea.
  • Le VH; Department of Mechanical Engineering, Chonnam National University, Gwangju 61186, Korea.
  • Nguyen KT; Department of Mechanical Engineering, Chonnam National University, Gwangju 61186, Korea.
  • Nguyen VD; Korea Institute of Medical Microrobotics, Gwangju 61186, Korea.
  • Kim J; Korea Institute of Medical Microrobotics, Gwangju 61186, Korea.
  • Choi E; Department of Mechanical Engineering, Chonnam National University, Gwangju 61186, Korea.
  • Bang S; Division of Gastroenterology, Department of Internal Medicine, Yonsei University College of Medicine, Seoul 120-752, Korea.
  • Kang B; Korea Institute of Medical Microrobotics, Gwangju 61186, Korea.
  • Park JO; Department of Mechanical Engineering, Chonnam National University, Gwangju 61186, Korea.
  • Kim CS; Department of Mechanical Engineering, Chonnam National University, Gwangju 61186, Korea.
Micromachines (Basel) ; 11(1)2020 Jan 17.
Article en En | MEDLINE | ID: mdl-31963402
Capsule endoscopes (CEs) have emerged as an advanced diagnostic technology for gastrointestinal diseases in recent decades. However, with regard to robotic motions, they require active movability and multi-functionalities for extensive, untethered, and precise clinical utilization. Herein, we present a novel wireless biopsy CE employing active five degree-of-freedom locomotion and a biopsy needle punching mechanism for the histological analysis of the intestinal tract. A medical biopsy punch is attached to a screw mechanism, which can be magnetically actuated to extrude and retract the biopsy tool, for tissue extraction. The external magnetic field from an electromagnetic actuation (EMA) system is utilized to actuate the screw mechanism and harvest biopsy tissue; therefore, the proposed system consumes no onboard energy of the CE. This design enables observation of the biopsy process through the capsule's camera. A prototype with a diameter of 12 mm and length of 30 mm was fabricated with a medical biopsy punch having a diameter of 1.5 mm. Its performance was verified through numerical analysis, as well as in-vitro and ex-vivo experiments on porcine intestine. The CE could be moved to target lesions and obtain sufficient tissue samples for histological examination. The proposed biopsy CE mechanism utilizing punch biopsy and its wireless extraction-retraction technique can advance untethered intestinal endoscopic capsule technology at clinical sites.
Palabras clave
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Micromachines (Basel) Año: 2020 Tipo del documento: Article Pais de publicación: Suiza
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Micromachines (Basel) Año: 2020 Tipo del documento: Article Pais de publicación: Suiza