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Evaluation of a semi-automatic isoelectric focusing method for apolipoprotein E phenotyping.
Bittar, Randa; Carrié, Alain; Nouadje, Georges; Cherfils, Corinne; Fesel-Fouquier, Valérie; Barbot-Trystram, Laurence; Giral, Philippe; Bonnefont-Rousselot, Dominique.
Afiliación
  • Bittar R; Service de Biochimie Métabolique, AP-HP.Sorbonne Université, F-75013, Paris, France.
  • Carrié A; Sorbonne Université, UMR_S1166 ICAN, F-75013, Paris, France.
  • Nouadje G; Sorbonne Université, UMR_S1166 ICAN, F-75013, Paris, France.
  • Cherfils C; Service de Biochimie Endocrinienne et Oncologique, AP-HP.Sorbonne Université, F-75013, Paris, France.
  • Fesel-Fouquier V; Sebia, F-91008, Evry, France.
  • Barbot-Trystram L; Service de Biochimie Métabolique, AP-HP.Sorbonne Université, F-75013, Paris, France.
  • Giral P; Service de Biochimie Métabolique, AP-HP.Sorbonne Université, F-75013, Paris, France.
  • Bonnefont-Rousselot D; Service de Coprologie Fonctionnelle, AP-HP.Sorbonne Université, F-75013, Paris, France.
Pract Lab Med ; 18: e00150, 2020 Jan.
Article en En | MEDLINE | ID: mdl-31909147
A qualitative, semi-automatized method for apolipoprotein E (apoE) phenotyping by isoelectric focusing method has been evaluated on 40 serum samples from patients previously genotyped for apoE, especially as regards concordance with genotyping, but also repeatability and reproducibility of the method, and sample storage. Total concordance with genotyping and good precision criteria, together with its practicability and requirement of a little sample volume, lead to conclude to the usefulness of this method to help clinicians in the diagnosis of dyslipidemic and neurodegenerative diseases.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Tipo de estudio: Qualitative_research Idioma: En Revista: Pract Lab Med Año: 2020 Tipo del documento: Article País de afiliación: Francia Pais de publicación: Países Bajos
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Tipo de estudio: Qualitative_research Idioma: En Revista: Pract Lab Med Año: 2020 Tipo del documento: Article País de afiliación: Francia Pais de publicación: Países Bajos