Your browser doesn't support javascript.
loading
Topical stabilized hypochlorous acid: The future gold standard for wound care and scar management in dermatologic and plastic surgery procedures.
Gold, Michael H; Andriessen, Anneke; Bhatia, Ashish C; Bitter, Patrick; Chilukuri, Suneel; Cohen, Joel L; Robb, Chris W.
Afiliación
  • Gold MH; Gold Skin Care Center, Nashville, TN, USA.
  • Andriessen A; Tennessee Clinical Research Center, Nashville, TN, USA.
  • Bhatia AC; Vanderbilt University School of Nursing, Nashville, TN, USA.
  • Bitter P; School of Medicine, Meharry Medical College, Nashville, TN, USA.
  • Chilukuri S; Andriessen Consultants & Radboud UMC, Nijmegen, The Netherlands.
  • Cohen JL; Northwestern University - Feinberg School of Medicine, Chicago, IL, USA.
  • Robb CW; Oak Dermatology, Itasca, IL, USA.
J Cosmet Dermatol ; 19(2): 270-277, 2020 Feb.
Article en En | MEDLINE | ID: mdl-31904191
BACKGROUND: Hypochlorous acid (HOCl), a naturally occurring molecule produced by the immune system, is highly active against bacterial, viral, and fungal microorganisms. Moreover, HOCl is active against biofilm and increases oxygenation of the wound site to improve healing. Natural HOCl is unstable; through technology, it can be stabilized into an effective topical antiseptic agent. AIM: This paper focuses on the use of topical stabilized HOCl in wound and scar management for pre-, peri-, and postprocedures-including its ability to reduce the occurrence hypertrophic scars and keloids. The role of the product in other skin conditions is beyond the scope of this article. METHODS: A panel comprising clinicians with experience in cosmetic and surgical procedures met late 2018 to discuss literature search results and their own current clinical experience regarding topical stabilized HOCl. The panel of key opinion leaders in dermatology and plastic surgery defined key insights and consensus statements on the direction of use for the product. RESULTS: Topical stabilized HOCl provides an optimal wound healing environment and, when combined with silicone, may be ideal for reducing scarring. Additionally, in contrast to chlorhexidine, HOCl, used as an antiseptic skin preparation, raises no concerns of ocular- or ototoxicity. CONCLUSIONS: For wound care and scar management, topical stabilized HOCl conveys powerful microbicidal and antibiofilm properties, in addition to potency as a topical wound healing agent. It may offer physicians an alternative to other less desirable wound care measures.
Asunto(s)
Palabras clave
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Infección de la Herida Quirúrgica / Cicatriz Hipertrófica / Ácido Hipocloroso / Procedimientos de Cirugía Plástica / Queloide / Antiinfecciosos Locales Tipo de estudio: Etiology_studies Límite: Humans Idioma: En Revista: J Cosmet Dermatol Asunto de la revista: DERMATOLOGIA Año: 2020 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Reino Unido
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Infección de la Herida Quirúrgica / Cicatriz Hipertrófica / Ácido Hipocloroso / Procedimientos de Cirugía Plástica / Queloide / Antiinfecciosos Locales Tipo de estudio: Etiology_studies Límite: Humans Idioma: En Revista: J Cosmet Dermatol Asunto de la revista: DERMATOLOGIA Año: 2020 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Reino Unido