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The application of enhanced recovery after surgery for upper gastrointestinal surgery: Meta-analysis.
Huang, Zhen-Dong; Gu, Hui-Yun; Zhu, Jie; Luo, Jie; Shen, Xian-Feng; Deng, Qi-Feng; Zhang, Chao; Li, Yan-Bing.
Afiliación
  • Huang ZD; Center for Evidence-Based Medicine and Clinical Research, Taihe Hospital, Hubei University of Medicine, No.32, South Renmin Road, Shiyan, 442000, China.
  • Gu HY; Department of Orthopedic, Zhongnan Hospital of Wuhan University, Wuhan University, Wuhan, 430000, China.
  • Zhu J; Trade Union, Taihe Hospital, Hubei University of Medicine, Shiyan, 442000, China.
  • Luo J; Center for Evidence-Based Medicine and Clinical Research, Taihe Hospital, Hubei University of Medicine, No.32, South Renmin Road, Shiyan, 442000, China.
  • Shen XF; Department of General Surgery, Taihe Hospital, Hubei University of Medicine, No.32, South Renmin Road, Shiyan, 442000, China.
  • Deng QF; Center for Evidence-Based Medicine and Clinical Research, Taihe Hospital, Hubei University of Medicine, No.32, South Renmin Road, Shiyan, 442000, China.
  • Zhang C; Center for Evidence-Based Medicine and Clinical Research, Taihe Hospital, Hubei University of Medicine, No.32, South Renmin Road, Shiyan, 442000, China. zhangchao0803@126.com.
  • Li YB; Department of General Surgery, Taihe Hospital, Hubei University of Medicine, No.32, South Renmin Road, Shiyan, 442000, China. liyanbing126@163.com.
BMC Surg ; 20(1): 3, 2020 Jan 03.
Article en En | MEDLINE | ID: mdl-31900149
BACKGROUND: Although enhanced recovery after surgery (ERAS) has made great progress in the field of surgery, the guidelines point to the lack of high-quality evidence in upper gastrointestinal surgery. METHODS: Randomized controlled trials in four electronic databases that involved ERAS protocols for upper gastrointestinal surgery were searched through December 12, 2018. The primary endpoints were lung infection, urinary tract infection, surgical site infection, postoperative anastomotic leakage and ileus. The secondary endpoints were postoperative length of stay, the time from end of surgery to first flatus and defecation, and readmission rates. Subgroup analysis was performed based on the type of surgery. RESULTS: A total of 17 studies were included. The results of the meta-analysis indicate that there was a decrease in rates of lung infection (RR = 0.50, 95%CI: 0.33 to 0.75), postoperative length of stay (MD = -2.53, 95%CI: - 3.42 to - 1.65), time until first postoperative flatus (MD = -0.64, 95%CI: - 0.84 to - 0.45) and time until first postoperative defecation (MD = -1.10, 95%CI: - 1.74 to - 0.47) in patients who received ERAS, compared to conventional care. However, other outcomes were not significant difference. There was no significant difference between ERAS and conventional care in rates of urinary tract infection (P = 0.10), surgical site infection (P = 0.42), postoperative anastomotic leakage (P = 0.45), readmissions (P = 0.31) and ileus (P = 0.25). CONCLUSIONS: ERAS protocols can reduce the risk of postoperative lung infection and accelerating patient recovery time. Nevertheless, we should also consider further research ERAS should be performed undergoing gastrectomy and esophagectomy.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Procedimientos Quirúrgicos del Sistema Digestivo / Recuperación Mejorada Después de la Cirugía Tipo de estudio: Clinical_trials / Systematic_reviews Límite: Humans Idioma: En Revista: BMC Surg Año: 2020 Tipo del documento: Article País de afiliación: China Pais de publicación: Reino Unido

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Procedimientos Quirúrgicos del Sistema Digestivo / Recuperación Mejorada Después de la Cirugía Tipo de estudio: Clinical_trials / Systematic_reviews Límite: Humans Idioma: En Revista: BMC Surg Año: 2020 Tipo del documento: Article País de afiliación: China Pais de publicación: Reino Unido