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Regulating germline editing in assisted reproductive technology: An EU cross-disciplinary perspective.
Nordberg, Ana; Minssen, Timo; Feeney, Oliver; de Miguel Beriain, Iñigo; Galvagni, Lucia; Wartiovaara, Kirmo.
Afiliación
  • Nordberg A; Faculty of Law, Lund University, Lund, Sweden.
  • Minssen T; Centre for Advanced Studies in Biomedical Innovation Law (CeBIL), University of Copenhagen, Copenhagen, Denmark.
  • Feeney O; School of Nursing and Midwifery, University College Cork, Cork, Ireland.
  • de Miguel Beriain I; UNESCO Bioethics Ireland, Centre of Bioethical Research and Analysis, National University of Ireland (Galway), Galway, Ireland.
  • Galvagni L; University of the Basque Country, Spain.
  • Wartiovaara K; Ikerbasque, Basque Foundation for Science, Bilbao, Spain.
Bioethics ; 34(1): 16-32, 2020 01.
Article en En | MEDLINE | ID: mdl-31877579
Potential applications of genome editing in assisted reproductive technology (ART) raise a vast array of strong opinions, emotional reactions and divergent perceptions. Acknowledging the need for caution and respecting such reactions, we observe that at least some are based on either a misunderstanding of the science or misconceptions about the content and flexibility of the existing legal frameworks. Combining medical, legal and ethical expertise, we present and discuss regulatory responses at the national, European and international levels. The discussion has an EU starting point and is meant as a contribution to the general international regulatory debate. Overall, this paper concludes that gene editing technologies should not be regulated autonomously. Rather, potential uses should be regulated under general, existing frameworks and where applicable by reference to sufficiently equivalent technologies and techniques already subject to specific regulation. To be clear, we do not argue for the hasty introduction of gene editing as a reproductive treatment option in the immediate future. We call for caution with regard to overreaching moratoria and prohibitions that will also affect basic research. We recommend flexible regulations that allow for further responsible research into the potential development of the technology. We call for an open and inclusive debate and argue that scientific communication should claim a more prominent role to counter the danger of widespread misinformation. A high level of transparency and accuracy should guide scientific communication while simultaneously global-scale responsibility and governance should be fostered by promoting cross-disciplinary thinking and multi-level stakeholder involvement in legal and regulatory processes.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Técnicas Reproductivas Asistidas / Edición Génica / Células Germinativas Tipo de estudio: Qualitative_research / Sysrev_observational_studies Aspecto: Ethics Límite: Humans Idioma: En Revista: Bioethics Asunto de la revista: ETICA Año: 2020 Tipo del documento: Article País de afiliación: Suecia Pais de publicación: Reino Unido

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Técnicas Reproductivas Asistidas / Edición Génica / Células Germinativas Tipo de estudio: Qualitative_research / Sysrev_observational_studies Aspecto: Ethics Límite: Humans Idioma: En Revista: Bioethics Asunto de la revista: ETICA Año: 2020 Tipo del documento: Article País de afiliación: Suecia Pais de publicación: Reino Unido