AMCase, acidic mammalian chitinase; BALF, bronchoalveolar lavage fluid; Bpifa1, bactericidal/permeability-increasing protein (BPI) fold-containing family A member 1; CF, cystic fibrosis; CFTR, cystic fibrosis transmembrane conductance regulator; CLCA1; CLCA1, calcium-activated chloride channel regulator 1; COPD, chronic obstructive pulmonary disease; CXCL-1, C-X-C motif chemokine ligand 1; CaCCs, calcium-activated chloride channels; Cancer; CeO2NPs, cerium dioxide nanoparticles; DOG1, discovered on gastrointestinal stromal tumours-1; DSS, dextran sodium sulfate; EGFR, epidermal growth factor receptor; EMT, epithelial-mesenchymal transition; ERK, extracellular signal-regulated kinase; EpOCs, epithelial organoid cultures; FAK, focal adhesion kinase; Gastrointestinal disease; Gob-5, goblet cell protein-5; HDMA, house dust mite allergen; IAD, inflammatory airway diseases; Innate immunity; KCNMB1, potassium calcium-activated channel subfamily M regulatory beta subunit 1; LFA-1, lymphocyte function-associated antigen 1.; LFC, log2 fold change; MUC5AC, mucin 5AC; Mucin; NFA, niflumic acid; OVA, ovalbumin; Respiratory diseases; SPDEF, sterile alpha motif [SAM] domain-containing prostate-derived Ets transcription factor; STAT6, signal transducer and activator of transcription 6; TMEM16A, transmembrane protein 16A; TNF-α, tumor necrosis factor-α; VWA, von Willebrand factor type A; WT, wild-type; cAMP, cyclic adenosine monophosphate; rIFABP, rat intestinal fatty acid binding protein promoter; ß4BMs, ß4-binding motifs