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Single-cell analysis uncovers that metabolic reprogramming by ErbB2 signaling is essential for cardiomyocyte proliferation in the regenerating heart.
Honkoop, Hessel; de Bakker, Dennis Em; Aharonov, Alla; Kruse, Fabian; Shakked, Avraham; Nguyen, Phong D; de Heus, Cecilia; Garric, Laurence; Muraro, Mauro J; Shoffner, Adam; Tessadori, Federico; Peterson, Joshua Craiger; Noort, Wendy; Bertozzi, Alberto; Weidinger, Gilbert; Posthuma, George; Grün, Dominic; van der Laarse, Willem J; Klumperman, Judith; Jaspers, Richard T; Poss, Kenneth D; van Oudenaarden, Alexander; Tzahor, Eldad; Bakkers, Jeroen.
Afiliación
  • Honkoop H; Hubrecht Institute-KNAW and University Medical Center Utrecht, Utrecht, Netherlands.
  • de Bakker DE; Hubrecht Institute-KNAW and University Medical Center Utrecht, Utrecht, Netherlands.
  • Aharonov A; Department of Molecular Cell Biology, Weizmann Institute of Science, Rehovot, Israel.
  • Kruse F; Hubrecht Institute-KNAW and University Medical Center Utrecht, Utrecht, Netherlands.
  • Shakked A; Department of Molecular Cell Biology, Weizmann Institute of Science, Rehovot, Israel.
  • Nguyen PD; Hubrecht Institute-KNAW and University Medical Center Utrecht, Utrecht, Netherlands.
  • de Heus C; Section Cell Biology, Center for Molecular Medicine, University Medical Center Utrecht, Utrecht University, Utrecht, Netherlands.
  • Garric L; Hubrecht Institute-KNAW and University Medical Center Utrecht, Utrecht, Netherlands.
  • Muraro MJ; Hubrecht Institute-KNAW and University Medical Center Utrecht, Utrecht, Netherlands.
  • Shoffner A; Regeneration Next, Department of Cell Biology, Duke University Medical Center, Durham, United States.
  • Tessadori F; Hubrecht Institute-KNAW and University Medical Center Utrecht, Utrecht, Netherlands.
  • Peterson JC; Laboratory for Myology, Department of Human Movement Sciences, Faculty of Behavioural and Movement Sciences, Vrije Universiteit Amsterdam, Amsterdam, Netherlands.
  • Noort W; Laboratory for Myology, Department of Human Movement Sciences, Faculty of Behavioural and Movement Sciences, Vrije Universiteit Amsterdam, Amsterdam, Netherlands.
  • Bertozzi A; Institute of Biochemistry and Molecular Biology, Ulm University, Ulm, Germany.
  • Weidinger G; Institute of Biochemistry and Molecular Biology, Ulm University, Ulm, Germany.
  • Posthuma G; Section Cell Biology, Center for Molecular Medicine, University Medical Center Utrecht, Utrecht University, Utrecht, Netherlands.
  • Grün D; Max Planck Institute of Immunobiology and Epigenetics, Freiburg, Germany.
  • van der Laarse WJ; Department of Physiology, Institute for Cardiovascular Research, VU University Medical Center, Amsterdam, Netherlands.
  • Klumperman J; Section Cell Biology, Center for Molecular Medicine, University Medical Center Utrecht, Utrecht University, Utrecht, Netherlands.
  • Jaspers RT; Laboratory for Myology, Department of Human Movement Sciences, Faculty of Behavioural and Movement Sciences, Vrije Universiteit Amsterdam, Amsterdam, Netherlands.
  • Poss KD; Regeneration Next, Department of Cell Biology, Duke University Medical Center, Durham, United States.
  • van Oudenaarden A; Hubrecht Institute-KNAW and University Medical Center Utrecht, Utrecht, Netherlands.
  • Tzahor E; Department of Molecular Cell Biology, Weizmann Institute of Science, Rehovot, Israel.
  • Bakkers J; Hubrecht Institute-KNAW and University Medical Center Utrecht, Utrecht, Netherlands.
Elife ; 82019 12 23.
Article en En | MEDLINE | ID: mdl-31868166
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Regeneración / Pez Cebra / Transducción de Señal / Miocitos Cardíacos / Proliferación Celular / Reprogramación Celular / Análisis de la Célula Individual / Corazón Tipo de estudio: Prognostic_studies Límite: Animals Idioma: En Revista: Elife Año: 2019 Tipo del documento: Article País de afiliación: Países Bajos Pais de publicación: Reino Unido
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Regeneración / Pez Cebra / Transducción de Señal / Miocitos Cardíacos / Proliferación Celular / Reprogramación Celular / Análisis de la Célula Individual / Corazón Tipo de estudio: Prognostic_studies Límite: Animals Idioma: En Revista: Elife Año: 2019 Tipo del documento: Article País de afiliación: Países Bajos Pais de publicación: Reino Unido