Intermittent hypoxia and bronchial hyperreactivity.
Semin Fetal Neonatal Med
; 25(2): 101073, 2020 04.
Article
en En
| MEDLINE
| ID: mdl-31862223
The premature neonate is at high risk for childhood airway hyperreactivity and episodes of wheezing. Intermittent hypoxic events are frequently observed during the first weeks and months of life in these infants. Intermittent hypoxemia has been associated with adverse outcomes in extremely premature infants; including the diagnosis of bronchopulmonary dysplasia, reported wheezing, and use of prescription asthma medications. We review the incidence of intermittent hypoxia, their potential role in short and longer term respiratory morbidity, and the translational newborn models now being used to investigate common pathways by which intermittent hypoxia contributes to respiratory disease.
Palabras clave
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Hiperreactividad Bronquial
/
Enfermedades del Prematuro
/
Hipoxia
Tipo de estudio:
Etiology_studies
/
Incidence_studies
/
Prognostic_studies
Límite:
Child
/
Humans
/
Infant
/
Newborn
Idioma:
En
Revista:
Semin Fetal Neonatal Med
Asunto de la revista:
PEDIATRIA
/
PERINATOLOGIA
Año:
2020
Tipo del documento:
Article
Pais de publicación:
Países Bajos