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Reinventing Neuroaging Research in the Digital Age.
Huentelman, Matt J; Talboom, Joshua S; Lewis, Candace R; Chen, Zhao; Barnes, Carol A.
Afiliación
  • Huentelman MJ; Neurogenomics Division, The Translational Genomics Research Institute, Phoenix, AZ, USA; The Arizona Alzheimer's Consortium, Phoenix, AZ, USA.
  • Talboom JS; Neurogenomics Division, The Translational Genomics Research Institute, Phoenix, AZ, USA; The Arizona Alzheimer's Consortium, Phoenix, AZ, USA.
  • Lewis CR; Neurogenomics Division, The Translational Genomics Research Institute, Phoenix, AZ, USA; The Arizona Alzheimer's Consortium, Phoenix, AZ, USA.
  • Chen Z; Department of Epidemiology and Biostatistics, University of Arizona, Tucson, AZ, USA.
  • Barnes CA; The Arizona Alzheimer's Consortium, Phoenix, AZ, USA; Evelyn F. McKnight Brain Institute and Department of Psychology, University of Arizona, Tucson, AZ, USA. Electronic address: carol@nsma.arizona.edu.
Trends Neurosci ; 43(1): 17-23, 2020 01.
Article en En | MEDLINE | ID: mdl-31848024
The worldwide average human lifespan has increased over the past century. These changing demographics demand a reinvention of experimental approaches to study the brain and aging, with the aim of better matching cognitive healthspan with human lifespan. Past studies of cognitive aging included sample sizes that tended to be underpowered, were not sufficiently representative of national population characteristics, and often lacked longitudinal assessments. As a step to address these shortcomings, we propose a framework that encourages interaction between electronic-based and face-to-face study designs. We argue that this will achieve the necessary synergy to accelerate progress in the discovery and application of personalized interventions to optimize brain and cognitive health.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Encéfalo / Envejecimiento / Neuroimagen Límite: Humans Idioma: En Revista: Trends Neurosci Año: 2020 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Reino Unido

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Encéfalo / Envejecimiento / Neuroimagen Límite: Humans Idioma: En Revista: Trends Neurosci Año: 2020 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Reino Unido