Do Mutations Turn p53 into an Oncogene?

Pitolli, Consuelo; Wang, Ying; Mancini, Mara; Shi, Yufang; Melino, Gerry; Amelio, Ivano

Pitolli, Consuelo; Wang, Ying; Mancini, Mara; Shi, Yufang; Melino, Gerry; Amelio, Ivano.

Afiliación

Pitolli C; Department of Experimental Medicine, TOR, University of Rome Tor Vergata, 00133 Rome, Italy.
Wang Y; MRC Toxicology Unit, University of Cambridge, Pathology Building, Tennis Court Road, Cambridge CB2 1PQ, UK.
Mancini M; CAS Key Laboratory of Tissue Microenvironment and Tumor, Institute of Nutrition and Health, University of Chinese Academy of Sciences, Chinese Academy of Sciences, Shanghai 100012, China.
Shi Y; Department of Experimental Medicine, TOR, University of Rome Tor Vergata, 00133 Rome, Italy.
Melino G; IDI-IRCCS, Biochemistry Laboratory, 00167 Rome, Italy.
Amelio I; CAS Key Laboratory of Tissue Microenvironment and Tumor, Institute of Nutrition and Health, University of Chinese Academy of Sciences, Chinese Academy of Sciences, Shanghai 100012, China.

Int J Mol Sci ; 20(24)2019 Dec 11.

Article en En | MEDLINE | ID: mdl-31835684

Asunto(s)

Mutación/genética; Oncogenes; Proteína p53 Supresora de Tumor/genética; Animales; Resistencia a Antineoplásicos/genética; Humanos; Neoplasias/genética; Neoplasias/patología; Hipoxia Tumoral/genética

Palabras clave

TP53; gain of function; mutant TP53; oncogenic

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Oncogenes / Proteína p53 Supresora de Tumor / Mutación Límite: Animals / Humans Idioma: En Revista: Int J Mol Sci Año: 2019 Tipo del documento: Article País de afiliación: Italia Pais de publicación: Suiza

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