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Verapamil decreases calpain-1 and matrix metalloproteinase-2 activities and improves hypertension-induced hypertrophic cardiac remodeling in rats.
Mendes, Atlante S; Blascke de Mello, Marcela M; Parente, Juliana M; Omoto, Ana Carolina M; Neto-Neves, Evandro M; Fazan, Rubens; Tanus-Santos, Jose E; Castro, Michele M.
Afiliación
  • Mendes AS; Department of Pharmacology, Ribeirao Preto Medical School, University of Sao Paulo, Av. Bandeirantes, 3900, 14049-900 Ribeirao Preto, SP, Brazil.
  • Blascke de Mello MM; Department of Pharmacology, Ribeirao Preto Medical School, University of Sao Paulo, Av. Bandeirantes, 3900, 14049-900 Ribeirao Preto, SP, Brazil.
  • Parente JM; Department of Pharmacology, Ribeirao Preto Medical School, University of Sao Paulo, Av. Bandeirantes, 3900, 14049-900 Ribeirao Preto, SP, Brazil.
  • Omoto ACM; Department of Physiology, Ribeirao Preto Medical School, University of Sao Paulo, Av. Bandeirantes, 3900, 14049-900 Ribeirao Preto, SP, Brazil.
  • Neto-Neves EM; Department of Pharmacology, Ribeirao Preto Medical School, University of Sao Paulo, Av. Bandeirantes, 3900, 14049-900 Ribeirao Preto, SP, Brazil.
  • Fazan R; Department of Physiology, Ribeirao Preto Medical School, University of Sao Paulo, Av. Bandeirantes, 3900, 14049-900 Ribeirao Preto, SP, Brazil.
  • Tanus-Santos JE; Department of Pharmacology, Ribeirao Preto Medical School, University of Sao Paulo, Av. Bandeirantes, 3900, 14049-900 Ribeirao Preto, SP, Brazil.
  • Castro MM; Department of Pharmacology, Ribeirao Preto Medical School, University of Sao Paulo, Av. Bandeirantes, 3900, 14049-900 Ribeirao Preto, SP, Brazil. Electronic address: castro@fmrp.usp.br.
Life Sci ; 244: 117153, 2020 Mar 01.
Article en En | MEDLINE | ID: mdl-31830479
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Calpaína / Verapamilo / Regulación de la Expresión Génica / Cardiomegalia / Remodelación Ventricular / Metaloproteinasa 2 de la Matriz / Hipertensión Tipo de estudio: Etiology_studies / Prognostic_studies Límite: Animals Idioma: En Revista: Life Sci Año: 2020 Tipo del documento: Article País de afiliación: Brasil Pais de publicación: Países Bajos
Texto completo
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XML
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Calpaína / Verapamilo / Regulación de la Expresión Génica / Cardiomegalia / Remodelación Ventricular / Metaloproteinasa 2 de la Matriz / Hipertensión Tipo de estudio: Etiology_studies / Prognostic_studies Límite: Animals Idioma: En Revista: Life Sci Año: 2020 Tipo del documento: Article País de afiliación: Brasil Pais de publicación: Países Bajos