Your browser doesn't support javascript.
loading
False lumen ejection fraction predicts growth in type B aortic dissection: preliminary results.
Burris, Nicholas S; Nordsletten, David A; Sotelo, Julio A; Grogan-Kaylor, Ross; Houben, Ignas B; Figueroa, C Alberto; Uribe, Sergio; Patel, Himanshu J.
Afiliación
  • Burris NS; Department of Radiology, University of Michigan, Ann Arbor, MI, USA.
  • Nordsletten DA; Department of Cardiac Surgery, University of Michigan, Ann Arbor, MI, USA.
  • Sotelo JA; Department of Biomedical Engineering, University of Michigan, Ann Arbor, MI, USA.
  • Grogan-Kaylor R; Biomedical Imaging Center, Pontificia Universidad Católica de Chile, Santiago, Chile.
  • Houben IB; Department of Electrical Engineering, Pontificia Universidad Católica de Chile, Santiago, Chile.
  • Figueroa CA; Millennium Nucleus for Cardiovascular Magnetic Resonance, Santiago, Chile.
  • Uribe S; Department of Radiology, University of Michigan, Ann Arbor, MI, USA.
  • Patel HJ; Department of Cardiac Surgery, University of Michigan, Ann Arbor, MI, USA.
Eur J Cardiothorac Surg ; 57(5): 896-903, 2020 05 01.
Article en En | MEDLINE | ID: mdl-31821480
OBJECTIVES: Current risk assessment strategies in type B aortic dissection are focused on anatomic parameters, although haemodynamic abnormalities that result in false lumen (FL) pressurization are thought to play a significant role in aortic growth. The objective of this study was to evaluate blood flow of the FL using 4D flow magnetic resonance imaging (MRI) and identify haemodynamic and anatomic factors that independently predict the rate of aortic growth. METHODS: Patients with dissection of the descending thoraco-abdominal aorta (n = 18) were enrolled in a prospective observational study and underwent 4D flow MRI for haemodynamic assessment of the entry tear and FL. Anatomic parameters were obtained by magnetic resonance angiography and baseline computed tomography. False lumen ejection fraction (FL EF) was defined the ratio of retrograde flow rate at the dominant entry tear during diastole over the antegrade systolic flow rate. RESULTS: The median aortic growth rate was 3.5 mm/year (interquartile range 0.5-8.1 mm/year). Entry tear peak velocity was lower in patients with enlarging aortic dimensions (95.5 ± 24.1 vs 128.1 ± 37.4 cm/s, P = 0.039). After adjusting for co-variates FL EF (ß = 0.15, P = 0.004), baseline maximal aortic diameter (ß = 0.37, P = 0.001) and the entry tear distance from the left subclavian artery (ß = 0.07, P = 0.016) were significant predictors of aortic growth rate. CONCLUSIONS: Beyond standard anatomic risk factors, FL EF is an independent predictor of aortic growth rate and may represent an intuitive, non-invasive method to estimate FL pressurization and improve patient-specific risk assessment in patients with type B aortic dissection.
Asunto(s)
Palabras clave
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Aneurisma de la Aorta Torácica / Implantación de Prótesis Vascular / Disección Aórtica Tipo de estudio: Observational_studies / Prognostic_studies / Risk_factors_studies Límite: Humans Idioma: En Revista: Eur J Cardiothorac Surg Asunto de la revista: CARDIOLOGIA Año: 2020 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Alemania
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Aneurisma de la Aorta Torácica / Implantación de Prótesis Vascular / Disección Aórtica Tipo de estudio: Observational_studies / Prognostic_studies / Risk_factors_studies Límite: Humans Idioma: En Revista: Eur J Cardiothorac Surg Asunto de la revista: CARDIOLOGIA Año: 2020 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Alemania