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Diagnostic performance of diffusion-weighted magnetic resonance imaging in assessing lymph node metastasis of esophageal cancer compared with PET.
Shuto, Kiyohiko; Kono, Tsuguaki; Shiratori, Toru; Akutsu, Yasunori; Uesato, Masaya; Mori, Mikito; Narushima, Kazuo; Imanishi, Shunsuke; Nabeya, Yoshihiro; Yanagawa, Noriyuki; Okazumi, Shinichi; Koda, Keiji; Matsubara, Hisahiro.
Afiliación
  • Shuto K; Department of Frontier Surgery, Chiba University Graduate School of Medicine, Chiba, Japan. kshuto@med.teikyo-u.ac.jp.
  • Kono T; Department of Surgery, Teikyo University Chiba Medical Center, Anesaki, 3426-3, Ichihara, Chiba, 299-0111, Japan. kshuto@med.teikyo-u.ac.jp.
  • Shiratori T; Department of Frontier Surgery, Chiba University Graduate School of Medicine, Chiba, Japan.
  • Akutsu Y; Department of Frontier Surgery, Chiba University Graduate School of Medicine, Chiba, Japan.
  • Uesato M; Department of Frontier Surgery, Chiba University Graduate School of Medicine, Chiba, Japan.
  • Mori M; Department of Frontier Surgery, Chiba University Graduate School of Medicine, Chiba, Japan.
  • Narushima K; Department of Frontier Surgery, Chiba University Graduate School of Medicine, Chiba, Japan.
  • Imanishi S; Department of Surgery, Teikyo University Chiba Medical Center, Anesaki, 3426-3, Ichihara, Chiba, 299-0111, Japan.
  • Nabeya Y; Department of Frontier Surgery, Chiba University Graduate School of Medicine, Chiba, Japan.
  • Yanagawa N; Department of Surgery, Teikyo University Chiba Medical Center, Anesaki, 3426-3, Ichihara, Chiba, 299-0111, Japan.
  • Okazumi S; Department of Surgery, Teikyo University Chiba Medical Center, Anesaki, 3426-3, Ichihara, Chiba, 299-0111, Japan.
  • Koda K; Department of Frontier Surgery, Chiba University Graduate School of Medicine, Chiba, Japan.
  • Matsubara H; Department of Radiology, Chiba University Graduate School of Medicine, Chiba, Japan.
Esophagus ; 17(3): 239-249, 2020 07.
Article en En | MEDLINE | ID: mdl-31820208
BACKGROUND: Although diffusion-weighted magnetic resonance imaging (DWI) for detecting lymph node (LN) metastasis is reported to be a successful modality for primary malignant tumors, there are few studies relating to esophageal cancer. This study aimed to clarify the diagnostic performance of DWI for assessing LN metastasis compared with positron emission tomography (PET) in patients with esophageal squamous cell cancer (eSCC). METHODS: Seventy-six patients with histologically proven eSCC who underwent curative esophagectomy without neoadjuvant treatment were reviewed retrospectively. Harvested LNs were divided into 1229 node stations with 94 metastases. Diagnostic abilities and prognostic significance were compared. RESULTS: In a station-by-station evaluation, the sensitivity was higher in DWI than PET (67% vs. 32%, P < 0.001). DWI showed more than 80% sensitivity for middle- and large-sized cancer nests and large area of cancer nests. The DWI-N0 group had a better 5-year relapse-free survival rate than the DWI-N+ group (78.5% vs. 34.2%, P < 0.001), as did the PET-N0 group. DWI-N status was an independent prognostic factor (hazard ratio [HR], 2.642; P = 0.048), as was PET-N status (HR 2.481; P = 0.033). CONCLUSIONS: DWI, which depends on cancer cell volume followed by elevated intranodal density, is a non-invasive modality and showed higher sensitivity than PET. It has clinical impact in predicting postoperative survival for patients with eSCC alongside its diagnostic ability and has significant performance in clinical practice.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Neoplasias Esofágicas / Imagen de Difusión por Resonancia Magnética / Tomografía de Emisión de Positrones / Carcinoma de Células Escamosas de Esófago / Metástasis Linfática Tipo de estudio: Diagnostic_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Límite: Adult / Aged / Aged80 / Female / Humans / Male / Middle aged Idioma: En Revista: Esophagus Año: 2020 Tipo del documento: Article País de afiliación: Japón Pais de publicación: Japón
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Neoplasias Esofágicas / Imagen de Difusión por Resonancia Magnética / Tomografía de Emisión de Positrones / Carcinoma de Células Escamosas de Esófago / Metástasis Linfática Tipo de estudio: Diagnostic_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Límite: Adult / Aged / Aged80 / Female / Humans / Male / Middle aged Idioma: En Revista: Esophagus Año: 2020 Tipo del documento: Article País de afiliación: Japón Pais de publicación: Japón