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The effectiveness of manipulation of fingers with Dupuytren's contracture 7 days after collagenase clostridial histolyticum injection.
Reynolds, Bethany; Tobin, Vicky; Smith, Julian A; Rozen, Warren M; Hunter-Smith, David J.
Afiliación
  • Reynolds B; Department of Plastic, Reconstructive and Hand Surgery, Peninsula Health, Frankston, Australia.
  • Tobin V; Peninsula Clinical School, Central Clinical School at Monash University, Melbourne, Australia.
  • Smith JA; Department of Plastic, Reconstructive and Hand Surgery, Peninsula Health, Frankston, Australia.
  • Rozen WM; Department of Surgery, Monash Medical Centre, Clayton, Australia.
  • Hunter-Smith DJ; Department of Plastic, Reconstructive and Hand Surgery, Peninsula Health, Frankston, Australia.
J Hand Surg Eur Vol ; 45(3): 286-291, 2020 Mar.
Article en En | MEDLINE | ID: mdl-31818174
Timing of manipulation of digits after collagenase injection for Dupuytren's disease varies and often takes place within the first few days post-injection. We prospectively investigated the effectiveness of performing manipulation under local anaesthesia 7 days after injection in 100 patients. Demographic data, passive extension deficit, and patient-reported outcome measures were recorded before collagenase injection. Four to 7 weeks after manipulation, passive extension deficit and patient-reported outcome measures improved significantly without the development of any tendon ruptures. Clinical success was achieved in 41% and clinical improvement in 76% of the patients. Adverse events were reported by 85%. The outcomes were comparable with studies with early manipulation, and demonstrate a safe and effective variation to current protocols. We conclude that delaying manipulation to 7 days after collagenase injection is safe and efficient, which allows for flexibility in clinical appointments without negatively affecting outcome. Level of evidence: III.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Traumatismos de los Tendones / Contractura de Dupuytren Tipo de estudio: Guideline Aspecto: Patient_preference Límite: Humans Idioma: En Revista: J Hand Surg Eur Vol Año: 2020 Tipo del documento: Article País de afiliación: Australia Pais de publicación: Reino Unido
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Traumatismos de los Tendones / Contractura de Dupuytren Tipo de estudio: Guideline Aspecto: Patient_preference Límite: Humans Idioma: En Revista: J Hand Surg Eur Vol Año: 2020 Tipo del documento: Article País de afiliación: Australia Pais de publicación: Reino Unido