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IL-17A promotes fatty acid uptake through the IL-17A/IL-17RA/p-STAT3/FABP4 axis to fuel ovarian cancer growth in an adipocyte-rich microenvironment.
Yu, Chunyan; Niu, Xiulong; Du, Yongrui; Chen, Yan; Liu, Xiaomei; Xu, Lingling; Iwakura, Yoichiro; Ma, Xiaoxia; Li, Yan; Yao, Zhi; Deng, Weimin.
Afiliación
  • Yu C; Department of Immunology, Tianjin Key Laboratory of Cellular and Molecular Immunology, Key Laboratory of Diseases and Microenvironment of Ministry of Education of China, Tianjin Medical University, No. 22 Qixiangtai Road, Heping District, Tianjin, 300070, China.
  • Niu X; Department of Prevention and Therapy of Skin Disease in the Security Environment, Characteristic Medical Center of Chinese People's Armed Police Force, Tianjin, 300162, China.
  • Du Y; Department of Reproductive Medicine, Tianjin Central Hospital of Gynecology Obstetrics, Tianjin, 300100, China.
  • Chen Y; Department of Immunology, Tianjin Key Laboratory of Cellular and Molecular Immunology, Key Laboratory of Diseases and Microenvironment of Ministry of Education of China, Tianjin Medical University, No. 22 Qixiangtai Road, Heping District, Tianjin, 300070, China.
  • Liu X; Department of Obstetrics and Gynecology, Tianjin Medical University General Hospital, Tianjin, 300052, China.
  • Xu L; Office of the Hospital Ethics Committee, Beijing Tiantan Hospital, Capital Medical University, Beijing, 100070, China.
  • Iwakura Y; Research Institute for Biomedical Sciences, Tokyo University of Science, Tokyo, 125-8585, Japan.
  • Ma X; Department of Immunology, Tianjin Key Laboratory of Cellular and Molecular Immunology, Key Laboratory of Diseases and Microenvironment of Ministry of Education of China, Tianjin Medical University, No. 22 Qixiangtai Road, Heping District, Tianjin, 300070, China.
  • Li Y; Department of Immunology, Tianjin Key Laboratory of Cellular and Molecular Immunology, Key Laboratory of Diseases and Microenvironment of Ministry of Education of China, Tianjin Medical University, No. 22 Qixiangtai Road, Heping District, Tianjin, 300070, China.
  • Yao Z; Department of Immunology, Tianjin Key Laboratory of Cellular and Molecular Immunology, Key Laboratory of Diseases and Microenvironment of Ministry of Education of China, Tianjin Medical University, No. 22 Qixiangtai Road, Heping District, Tianjin, 300070, China.
  • Deng W; Department of Immunology, Tianjin Key Laboratory of Cellular and Molecular Immunology, Key Laboratory of Diseases and Microenvironment of Ministry of Education of China, Tianjin Medical University, No. 22 Qixiangtai Road, Heping District, Tianjin, 300070, China. dengweimin@tmu.edu.cn.
Cancer Immunol Immunother ; 69(1): 115-126, 2020 Jan.
Article en En | MEDLINE | ID: mdl-31802182
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Neoplasias Ováricas / Adipocitos / Ácido Palmítico / Interleucina-17 Tipo de estudio: Prognostic_studies Límite: Animals / Female / Humans / Middle aged Idioma: En Revista: Cancer Immunol Immunother Asunto de la revista: ALERGIA E IMUNOLOGIA / NEOPLASIAS / TERAPEUTICA Año: 2020 Tipo del documento: Article País de afiliación: China Pais de publicación: Alemania
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Neoplasias Ováricas / Adipocitos / Ácido Palmítico / Interleucina-17 Tipo de estudio: Prognostic_studies Límite: Animals / Female / Humans / Middle aged Idioma: En Revista: Cancer Immunol Immunother Asunto de la revista: ALERGIA E IMUNOLOGIA / NEOPLASIAS / TERAPEUTICA Año: 2020 Tipo del documento: Article País de afiliación: China Pais de publicación: Alemania