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Precision Medicine and the Practice of Trichiatry: Adapting the Concept.
Trüeb, Ralph M; Jolliffe, Vicky M L; Régnier, Antonia Fellas; Dutra Rezende, Hudson; Vañó-Galván, Sergio; Kopera, Daisy; Ioannides, Demetrios; Gavazzoni Dias, Maria Fernanda Reis; Macpherson, Melanie; Gadzhigoroeva, Aida; Ovcharenko, Julya; Lee, Won-Soo; Murugusundram, Sundaram; Kurata, Sotaro; Chang, Mimi; Tanglertsampan, Chuchai.
Afiliación
  • Trüeb RM; Center for Dermatology and Hair Diseases Professor Trüeb, University of Zurich, Zurich, Switzerland.
  • Jolliffe VML; The Royal London Hospital, London, United Kingdom.
  • Régnier AF; Center for Dermatology and Hair Diseases Professor Trüeb, University of Zurich, Zurich, Switzerland.
  • Dutra Rezende H; Center for Dermatology and Hair Diseases Professor Trüeb, University of Zurich, Zurich, Switzerland.
  • Vañó-Galván S; Ramon y Cajal Hospital, University of Alcala, Madrid, Spain.
  • Kopera D; Center of Aesthetic Medicine, Department of Dermatology, Medical University Graz, Graz, Austria.
  • Ioannides D; 1st Department of Dermatology-Venereology, Aristotle University Medical School, Hospital of Skin and Venereal Diseases, Thessaloniki, Greece.
  • Gavazzoni Dias MFR; Department of Dermatology, Centro de Ciências Médicas, Hospital Universitário Antonia Pedro, Universidade Federal Fluminense, Niterói, Brazil.
  • Macpherson M; Department of Dermatology and Venereology, San Gabriel Clinic, Lima, Peru.
  • Gadzhigoroeva A; Moscow Scientific and Practical Center of Dermatology and Cosmetology of the Moscow City Health Department, Moscow, Russian Federation.
  • Ovcharenko J; General and Clinical Immunology and Allergology Department, School of Medicine, V.N. Karazin Kharkiv National University, Kharkiv, Ukraine.
  • Lee WS; Department of Dermatology, Yonsei University, Wonju College of Medicine, Wonju, Republic of Korea.
  • Murugusundram S; Chennai Skin Foundation & Yesudian Research Institute, Chennai, India.
  • Kurata S; Beppu Garden Hill Clinic & Kurata Clinic, Beppu City, Japan.
  • Chang M; Prince of Wales Hospital and the Chinese University of Hong Kong, Hong Kong, China.
  • Tanglertsampan C; Department of Dermatology, Mae Fah Luang University Hospital (Bangkok), Bumrungrad International Hospital, Bangkok, Thailand.
Skin Appendage Disord ; 5(6): 338-343, 2019 Nov.
Article en En | MEDLINE | ID: mdl-31799259
Evidence-based medicine (EBM) aims for the ideal that healthcare professionals make conscientious, explicit, and judicious use of the best available evidence gained from the scientific method to clinical decision-making. It seeks to assess the strength of the evidence for benefits of diagnostic tests and treatments, using techniques from science, engineering, and statistics, such as the systematic review of medical literature, meta-analysis, risk-benefit analysis, and randomized controlled trials. The limited success rate of EBM therapies suggests that the complex nature of hair loss may be inadequately served by the present levels of evidence, and that physicians treating hair loss may have fallen short of adequately researching a robust evidence to underpin their practices. Against this backdrop, the concept of precision medicine (PM) is evolving. PM refers to the customization of medical care to the patient's individual characteristics based on the patient's genetic background and other molecular or cellular analysis, while classifying patients into subpopulations that differ in their susceptibility to a particular medical condition, in the biology or prognosis of those medical conditions, or in their response to a specific treatment. With the advances in hair research, the powerful tools of molecular biology and genetics, and innovative technologies, we have the robust scientific data and tools to adapt the concept of PM to the practice of trichiatry. Finally, databases pertaining to the development and efficacy of PM must be analyzed and be used to form the basis of evidence-based personalized trichiatry.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Tipo de estudio: Clinical_trials / Prognostic_studies / Systematic_reviews Idioma: En Revista: Skin Appendage Disord Año: 2019 Tipo del documento: Article País de afiliación: Suiza Pais de publicación: Suiza
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Tipo de estudio: Clinical_trials / Prognostic_studies / Systematic_reviews Idioma: En Revista: Skin Appendage Disord Año: 2019 Tipo del documento: Article País de afiliación: Suiza Pais de publicación: Suiza