Effects of crocin and saffron aqueous extract on gene expression of SIRT1, AMPK, LOX1, NF-&#954;B, and MCP-1 in patients with coronary artery disease: A randomized placebo-controlled clinical trial.

Abedimanesh, Nasim; Motlagh, Behrooz; Abedimanesh, Saeed; Bathaie, S Zahra; Separham, Ahmad; Ostadrahimi, Alireza

Effects of crocin and saffron aqueous extract on gene expression of SIRT1, AMPK, LOX1, NF-κB, and MCP-1 in patients with coronary artery disease: A randomized placebo-controlled clinical trial.

Abedimanesh, Nasim; Motlagh, Behrooz; Abedimanesh, Saeed; Bathaie, S Zahra; Separham, Ahmad; Ostadrahimi, Alireza.

Afiliación

Abedimanesh N; Department of Nutrition, School of Medicine, Zanjan University of Medical Sciences, Zanjan, Iran.
Motlagh B; Department of Clinical Biochemistry, School of Medicine, Zanjan University of Medical Sciences, Zanjan, Iran.
Abedimanesh S; Faculty of Medical Sciences, Department of Clinical Biochemistry, Tarbiat Modares University, Tehran, Iran.
Bathaie SZ; Faculty of Medical Sciences, Department of Clinical Biochemistry, Tarbiat Modares University, Tehran, Iran.
Separham A; Cardiovascular Research Center, Tabriz University of Medical Sciences, Tabriz, Iran.
Ostadrahimi A; Nutrition Research Center, Tabriz University of Medical Sciences, Tabriz, Iran.

Phytother Res ; 34(5): 1114-1122, 2020 May.

Article en En | MEDLINE | ID: mdl-31797473

Asunto(s)

Carotenoides/química; Quimiocina CCL2/metabolismo; Enfermedad de la Arteria Coronaria/tratamiento farmacológico; Crocus/química; FN-kappa B/metabolismo; Sirtuina 1/química; Adulto; Anciano; Femenino; Expresión Génica; Humanos; Masculino; Persona de Mediana Edad; Sirtuina 1/metabolismo

Palabras clave

AMPK; LOX1; NF-κB; SIRT1; coronary artery disease; crocin

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Enfermedad de la Arteria Coronaria / Carotenoides / FN-kappa B / Quimiocina CCL2 / Crocus / Sirtuina 1 Tipo de estudio: Clinical_trials Límite: Adult / Aged / Female / Humans / Male / Middle aged Idioma: En Revista: Phytother Res Asunto de la revista: TERAPIAS COMPLEMENTARES Año: 2020 Tipo del documento: Article País de afiliación: Irán Pais de publicación: Reino Unido

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