Your browser doesn't support javascript.
loading
Educational weight loss interventions in obese and overweight adults with type 2 diabetes: a systematic review and meta-analysis of randomized controlled trials.
Maula, A; Kai, J; Woolley, A K; Weng, S; Dhalwani, N; Griffiths, F E; Khunti, K; Kendrick, D.
Afiliación
  • Maula A; Division of Primary Care, School of Medicine, The University of Nottingham, Nottingham, UK.
  • Kai J; Division of Primary Care, School of Medicine, The University of Nottingham, Nottingham, UK.
  • Woolley AK; Leicester Diabetes Research Centre, University of Leicester, Leicester, UK.
  • Weng S; Division of Primary Care, School of Medicine, The University of Nottingham, Nottingham, UK.
  • Dhalwani N; Leicester Diabetes Research Centre, University of Leicester, Leicester, UK.
  • Griffiths FE; Real World Evidence, Evidera, London, UK.
  • Khunti K; Division of Health Sciences, Warwick Medical School, University of Warwick, Coventry, UK.
  • Kendrick D; School of Public Health, University of Witwatersrand, Johannesburg, South Africa.
Diabet Med ; 37(4): 623-635, 2020 04.
Article en En | MEDLINE | ID: mdl-31785118
AIM: The worldwide prevalence of type 2 diabetes mellitus is increasing, with most individuals with the disease being overweight or obese. Weight loss can reduce disease-related morbidity and mortality and weight losses of 10-15 kg have been shown to reverse type 2 diabetes. This review aimed to determine the effectiveness of community-based educational interventions for weight loss in type 2 diabetes. METHODS: This is a systematic review and meta-analysis of randomized controlled trials (RCT) in obese or overweight adults, aged 18-75 years, with a diagnosis of type 2 diabetes. Primary outcomes were weight and/or BMI. CINAHL, MEDLINE, Embase, Scopus and the Cochrane Central Register of Controlled Trials (CENTRAL) were searched from inception to June 2019. Trials were classified into specified a priori comparisons according to intervention type. A pooled standardized mean difference (SMD) (from baseline to follow-up) and 95% confidence intervals (95% CI) between trial groups (difference-in-difference) were estimated through random-effects meta-analyses using the inverse variance method. Heterogeneity was quantified using I2 and publication bias was explored visually using funnel plots. RESULTS: Some 7383 records were screened; 228 full-text articles were assessed and 49 RCTs (n = 12 461 participants) were included in this review, with 44 being suitable for inclusion into the meta-analysis. Pooled estimates of education combined with low-calorie, low-carbohydrate meal replacements (SMD = -2.48, 95% CI -3.59, -1.49, I2  = 98%) or diets (SMD = -1.25, 95% CI -2.11, -0.39, I2  = 95%) or low-fat meal replacements (SMD = -1.15, 95%CI -2.05, -1.09, I2  = 85%) appeared most effective. CONCLUSION: Low-calorie, low-carbohydrate meal replacements or diets combined with education appear the most promising interventions to achieve the largest weight and BMI reductions in people with type 2 diabetes.
Asunto(s)

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Educación del Paciente como Asunto / Diabetes Mellitus Tipo 2 / Sobrepeso / Programas de Reducción de Peso / Obesidad Tipo de estudio: Clinical_trials / Risk_factors_studies / Systematic_reviews Límite: Adolescent / Adult / Aged / Female / Humans / Male / Middle aged Idioma: En Revista: Diabet Med Asunto de la revista: ENDOCRINOLOGIA Año: 2020 Tipo del documento: Article Pais de publicación: Reino Unido

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Educación del Paciente como Asunto / Diabetes Mellitus Tipo 2 / Sobrepeso / Programas de Reducción de Peso / Obesidad Tipo de estudio: Clinical_trials / Risk_factors_studies / Systematic_reviews Límite: Adolescent / Adult / Aged / Female / Humans / Male / Middle aged Idioma: En Revista: Diabet Med Asunto de la revista: ENDOCRINOLOGIA Año: 2020 Tipo del documento: Article Pais de publicación: Reino Unido