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Granulomatosis with polyangiitis with breast involvement mimicking metastatic cancer: Case report and literature review.
Gadeyne, Laura; Henckaerts, Liesbet; Goffin, Karolien E; Gheysens, Olivier; Lerut, Evelyne; Roskams, Tania; Blockmans, Daniel; Floris, Giuseppe.
Afiliación
  • Gadeyne L; Department of Imaging and Pathology, KU Leuven, Leuven, Belgium.
  • Henckaerts L; Department of Pathology, University Hospitals Leuven, Leuven, Belgium.
  • Goffin KE; Department of Microbiology and Immunology, KU Leuven, Leuven, Belgium.
  • Gheysens O; Department of General Internal Medicine, University Hospitals Leuven, Leuven, Belgium.
  • Lerut E; Department of Imaging and Pathology, KU Leuven, Leuven, Belgium.
  • Roskams T; Department of Nuclear Medicine and Molecular Imaging, University Hospitals Leuven, Belgium.
  • Blockmans D; Department of Imaging and Pathology, KU Leuven, Leuven, Belgium.
  • Floris G; Department of Nuclear Medicine and Molecular Imaging, University Hospitals Leuven, Belgium.
Eur J Rheumatol ; 7(1): 41-43, 2020 01.
Article en En | MEDLINE | ID: mdl-31782722
Granulomatosis with polyangiitis (GPA) is a systemic inflammatory disease, characterized by the presence of necrotizing vasculitis of small and medium-sized vessels, granulomatous inflammation and anti-neutrophil cytoplasmic antibodies (ANCAs). The diagnosis can be challenging due to the variable clinical presentation and possible involvement of virtually all organ systems. A correct diagnosis is indispensable for a timely start of medical treatment and to avoid unnecessary surgery. Therefore, cooperation with and the input of the pathologist is crucial. We report a case of a woman presenting with suspected metastatic cancer. The diagnosis of GPA was made mainly based on breast biopsy, and the patient was treated accordingly, with full recovery. This report provides a case description and a brief review of the literature.

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Eur J Rheumatol Año: 2020 Tipo del documento: Article País de afiliación: Bélgica Pais de publicación: Turquía

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Eur J Rheumatol Año: 2020 Tipo del documento: Article País de afiliación: Bélgica Pais de publicación: Turquía