Applications and analysis of targeted genomic sequencing in cancer studies.

Bewicke-Copley, Findlay; Arjun Kumar, Emil; Palladino, Giuseppe; Korfi, Koorosh; Wang, Jun

Bewicke-Copley, Findlay; Arjun Kumar, Emil; Palladino, Giuseppe; Korfi, Koorosh; Wang, Jun.

Afiliación

Bewicke-Copley F; Centre for Cancer Genomics and Computational Biology, Barts Cancer Institute, Queen Mary University of London, Charterhouse Square, London EC1M 6BQ, UK.
Arjun Kumar E; Centre for Cancer Genomics and Computational Biology, Barts Cancer Institute, Queen Mary University of London, Charterhouse Square, London EC1M 6BQ, UK.
Palladino G; Centre for Haemato-Oncology, Barts Cancer Institute, Queen Mary University of London, Charterhouse Square, London EC1M 6BQ, UK.
Korfi K; Centre for Haemato-Oncology, Barts Cancer Institute, Queen Mary University of London, Charterhouse Square, London EC1M 6BQ, UK.
Wang J; Centre for Cancer Genomics and Computational Biology, Barts Cancer Institute, Queen Mary University of London, Charterhouse Square, London EC1M 6BQ, UK.

Comput Struct Biotechnol J ; 17: 1348-1359, 2019.

Article en En | MEDLINE | ID: mdl-31762958

Palabras clave

BAM, Binary Alignment Map; BWA, Burrows-Wheeler Aligner; Background error; CLL, Chronic Lymphocytic Leukaemia; COSMIC, Catalogue of Somatic Mutations in Cancer; Cancer genomics; Clinical samples; ESP, Exome Sequencing Project; FF, Fresh Frozen; FFPE, Formalin Fixed Paraffin Embedded; FL, Follicular Lymphoma; GATK, Genome Analysis Toolkit; ICGC, International Cancer Genome Consortium; MBC, Molecular Barcode; NCCN, the National Comprehensive Cancer Network®; NGS, Next Generation Sequencing; NHL, Non-Hodgkin Lymphoma; NSCLC, Non-Small Cell Lung Carcinoma; PCR duplicates; QC, Quality Control; SAM, Sequence Alignment Map; TCGA, The Cancer Genome Atlas; TS, Targeted Sequencing; Targeted sequencing; UMI, Unique Molecular Identifiers; VAF, Variant Allele Frequency; Variant calling; WES, Whole Exome Sequencing; WGS, Whole Genome Sequencing; tFL, Transformed Follicular Lymphoma

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Tipo de estudio: Guideline Idioma: En Revista: Comput Struct Biotechnol J Año: 2019 Tipo del documento: Article País de afiliación: Reino Unido Pais de publicación: Países Bajos

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