Pre-school child blood lead levels in a population-derived Australian birth cohort: the Barwon Infant Study.

Symeonides, Christos; Vuillermin, Peter; Sly, Peter D; Collier, Fiona; Lynch, Victoria; Falconer, Sandra; Pezic, Angela; Wardrop, Nicole; Dwyer, Terence; Ranganathan, Sarath; Ponsonby, Anne-Louise B

Symeonides, Christos; Vuillermin, Peter; Sly, Peter D; Collier, Fiona; Lynch, Victoria; Falconer, Sandra; Pezic, Angela; Wardrop, Nicole; Dwyer, Terence; Ranganathan, Sarath; Ponsonby, Anne-Louise B.

Afiliación

Symeonides C; Murdoch Children's Research Institute, Melbourne, VIC.
Vuillermin P; Royal Children's Hospital Melbourne, Melbourne, VIC.
Sly PD; Barwon Health, Geelong, VIC.
Collier F; Deakin University, Geelong, VIC.
Lynch V; Child Health Research Centre, University of Queensland, Brisbane, QLD.
Falconer S; WHO Collaborating Centre for Children's Health and Environment, University of Queensland, Brisbane, QLD.
Pezic A; Barwon Health, Geelong, VIC.
Wardrop N; Deakin University, Geelong, VIC.
Dwyer T; Victoria Department of Health and Human Services, Melbourne, VIC.
Ranganathan S; Victoria Department of Health and Human Services, Melbourne, VIC.
Ponsonby AB; Murdoch Children's Research Institute, Melbourne, VIC.

Med J Aust ; 212(4): 169-174, 2020 03.

Article en En | MEDLINE | ID: mdl-31760661

RESUMEN

OBJECTIVES: To investigate blood lead levels in an Australian birth cohort of children; to identify factors associated with higher lead levels. DESIGN, SETTING: Cross-sectional study within the Barwon Infant Study, a population birth cohort study in the Barwon region of Victoria (1074 infants, recruited June 2010 - June 2013). Data were adjusted for non-participation and attrition by propensity weighting. PARTICIPANTS: Blood lead was measured in 523 of 708 children appraised in the Barwon Infant Study pre-school review (mean age, 4.2 years; SD, 0.3 years). MAIN OUTCOME MEASURE: Blood lead concentration in whole blood (µg/dL). RESULTS: The median blood lead level was 0.8 µg/dL (range, 0.2-3.7 µg/dL); the geometric mean blood lead level after propensity weighting was 0.97 µg/dL (95% CI, 0.92-1.02 µg/dL). Children in houses 50 or more years old had higher blood lead levels (adjusted mean difference [AMD], 0.13 natural log units; 95% CI, 0.02-0.24 natural log units; P = 0.020), as did children of families with lower household income (per $10 000, AMD, -0.035 natural log units; 95% CI, -0.056 to -0.013 natural log units; P = 0.002) and those living closer to Point Henry (inverse square distance relationship; P = 0.002). Associations between hygiene factors and lead levels were evident only for children living in older homes. CONCLUSION: Blood lead levels in our pre-school children were lower than in previous Australian surveys and recent surveys in areas at risk of higher exposure, and no children had levels above 5 µg/dL. Our findings support advice to manage risks related to exposure to historical lead, especially in older houses.

Asunto(s)

Exposición a Riesgos Ambientales/análisis; Vivienda; Plomo/sangre; Australia; Niño; Preescolar; Estudios de Cohortes; Estudios Transversales; Femenino; Humanos; Modelos Lineales; Masculino; Análisis Multivariante; Factores Socioeconómicos

Palabras clave

Air pollutants; Environmental pollution; Epidemiology; Lead; Longitudinal studies; Public health; Socioeconomic factors

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Exposición a Riesgos Ambientales / Vivienda / Plomo Tipo de estudio: Etiology_studies / Incidence_studies / Observational_studies / Prevalence_studies / Prognostic_studies / Risk_factors_studies Aspecto: Determinantes_sociais_saude / Equity_inequality Límite: Child / Child, preschool / Female / Humans / Male País/Región como asunto: Oceania Idioma: En Revista: Med J Aust Año: 2020 Tipo del documento: Article Pais de publicación: Australia

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