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Outcome of patients with breast cancer in the oldest old (≥80 years).
Fleurier, Claire; De Wit, Adeline; Pilloy, Joseph; Boivin, Laura; Jourdan, Marie-Lise; Arbion, Flavie; Body, Gilles; Ouldamer, Lobna.
Afiliación
  • Fleurier C; Gynecology Department, Centre Hospitalier Régional Universitaire de Tours, Hôpital Bretonneau, 2 boulevard Tonnellé, 37044 Tours, France; François Rabelais University, Faculté de Médecine de Tours, 10 boulevard Tonnellé, 37044 Tours, France.
  • De Wit A; Gynecology Department, Centre Hospitalier Régional Universitaire de Tours, Hôpital Bretonneau, 2 boulevard Tonnellé, 37044 Tours, France; François Rabelais University, Faculté de Médecine de Tours, 10 boulevard Tonnellé, 37044 Tours, France.
  • Pilloy J; Gynecology Department, Centre Hospitalier Régional Universitaire de Tours, Hôpital Bretonneau, 2 boulevard Tonnellé, 37044 Tours, France; François Rabelais University, Faculté de Médecine de Tours, 10 boulevard Tonnellé, 37044 Tours, France.
  • Boivin L; Gynecology Department, Centre Hospitalier Régional Universitaire de Tours, Hôpital Bretonneau, 2 boulevard Tonnellé, 37044 Tours, France; François Rabelais University, Faculté de Médecine de Tours, 10 boulevard Tonnellé, 37044 Tours, France.
  • Jourdan ML; INSERM UMR1069, 10 boulevard Tonnellé, 37044 Tours, France; Centre Hospitalier Régional Universitaire de Tours, Hôpital Bretonneau, 2 boulevard Tonnellé, 37044 Tours, France.
  • Arbion F; Histology Department, Centre Hospitalier Régional Universitaire de Tours, Hôpital Bretonneau, 2 boulevard Tonnellé, 37044 Tours, France.
  • Body G; Gynecology Department, Centre Hospitalier Régional Universitaire de Tours, Hôpital Bretonneau, 2 boulevard Tonnellé, 37044 Tours, France; François Rabelais University, Faculté de Médecine de Tours, 10 boulevard Tonnellé, 37044 Tours, France; INSERM UMR1069, 10 boulevard Tonnellé, 37044 Tours, France
  • Ouldamer L; Gynecology Department, Centre Hospitalier Régional Universitaire de Tours, Hôpital Bretonneau, 2 boulevard Tonnellé, 37044 Tours, France; François Rabelais University, Faculté de Médecine de Tours, 10 boulevard Tonnellé, 37044 Tours, France; INSERM UMR1069, 10 boulevard Tonnellé, 37044 Tours, France
Eur J Obstet Gynecol Reprod Biol ; 244: 66-70, 2020 Jan.
Article en En | MEDLINE | ID: mdl-31760264
PURPOSE: In the present study, we present a large institutional study to determine the influence of age≥ 80 years on breast cancer presentation and prognosis. METHODS: The study is a retrospective analysis of our prospectively maintained breast cancer database study using data from of women managed from January 2007 through December 2013. Clinicopathologic characteristics were correlated with outcomes according to age (<80 years and ≥ 80 years). RESULTS: During the study period, 2083 women with invasive breast cancer were included of which 160 women aged ≥ 80 years (7.7 %). Overall survival was lower in the oldest old than in younger counterparts (p < 0.0001) as was distant metastasis free survival (p = 0.004). Differences in management included more radical surgeries and less chemotherapy and radiotherapy in case of age≥ 80 years. By multivariate analysis, age ≥ 80 years was an independent predictive factor of poor overall survival. CONCLUSION: In the present study, age ≥ 80 years was an independent predictive factor of poor overall survival.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Neoplasias de la Mama / Carcinoma Lobular / Carcinoma Ductal de Mama Tipo de estudio: Observational_studies / Prognostic_studies / Risk_factors_studies Límite: Adult / Aged / Aged80 / Humans / Middle aged País/Región como asunto: Europa Idioma: En Revista: Eur J Obstet Gynecol Reprod Biol Año: 2020 Tipo del documento: Article País de afiliación: Francia Pais de publicación: Irlanda
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Neoplasias de la Mama / Carcinoma Lobular / Carcinoma Ductal de Mama Tipo de estudio: Observational_studies / Prognostic_studies / Risk_factors_studies Límite: Adult / Aged / Aged80 / Humans / Middle aged País/Región como asunto: Europa Idioma: En Revista: Eur J Obstet Gynecol Reprod Biol Año: 2020 Tipo del documento: Article País de afiliación: Francia Pais de publicación: Irlanda