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Generation of highly potent DYRK1A-dependent inducers of human ß-Cell replication via Multi-Dimensional compound optimization.
Allegretti, Paul A; Horton, Timothy M; Abdolazimi, Yassan; Moeller, Hannah P; Yeh, Benjamin; Caffet, Matthew; Michel, Guillermina; Smith, Mark; Annes, Justin P.
Afiliación
  • Allegretti PA; Department of Medicine and Division of Endocrinology, Stanford University, Stanford, CA 94305, USA; Stanford ChEM-H, Stanford University, Stanford, CA 94305, USA.
  • Horton TM; Department of Medicine and Division of Endocrinology, Stanford University, Stanford, CA 94305, USA; Stanford ChEM-H, Stanford University, Stanford, CA 94305, USA; Department of Chemistry, Stanford University, Stanford, CA 94305, USA.
  • Abdolazimi Y; Department of Medicine and Division of Endocrinology, Stanford University, Stanford, CA 94305, USA.
  • Moeller HP; Department of Chemical and Systems Biology, Stanford University, Stanford, CA 94305, USA; Department of Medicine and Division of Endocrinology, Stanford University, Stanford, CA 94305, USA.
  • Yeh B; Department of Medicine and Division of Endocrinology, Stanford University, Stanford, CA 94305, USA.
  • Caffet M; Stanford ChEM-H, Stanford University, Stanford, CA 94305, USA.
  • Michel G; Department of Medicine and Division of Endocrinology, Stanford University, Stanford, CA 94305, USA.
  • Smith M; Stanford ChEM-H, Stanford University, Stanford, CA 94305, USA.
  • Annes JP; Department of Medicine and Division of Endocrinology, Stanford University, Stanford, CA 94305, USA; Stanford ChEM-H, Stanford University, Stanford, CA 94305, USA; Stanford Diabetes Research Center, Stanford University, Stanford, CA 94305, USA. Electronic address: Jannes@stanford.edu.
Bioorg Med Chem ; 28(1): 115193, 2020 01 01.
Article en En | MEDLINE | ID: mdl-31757680
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Proteínas Tirosina Quinasas / Proteínas Serina-Treonina Quinasas / Inhibidores de Proteínas Quinasas / Bibliotecas de Moléculas Pequeñas Límite: Humans Idioma: En Revista: Bioorg Med Chem Asunto de la revista: BIOQUIMICA / QUIMICA Año: 2020 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Reino Unido
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Proteínas Tirosina Quinasas / Proteínas Serina-Treonina Quinasas / Inhibidores de Proteínas Quinasas / Bibliotecas de Moléculas Pequeñas Límite: Humans Idioma: En Revista: Bioorg Med Chem Asunto de la revista: BIOQUIMICA / QUIMICA Año: 2020 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Reino Unido