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Genome-wide association study of eosinophilic granulomatosis with polyangiitis reveals genomic loci stratified by ANCA status.
Lyons, Paul A; Peters, James E; Alberici, Federico; Liley, James; Coulson, Richard M R; Astle, William; Baldini, Chiara; Bonatti, Francesco; Cid, Maria C; Elding, Heather; Emmi, Giacomo; Epplen, Jörg; Guillevin, Loïc; Jayne, David R W; Jiang, Tao; Gunnarsson, Iva; Lamprecht, Peter; Leslie, Stephen; Little, Mark A; Martorana, Davide; Moosig, Frank; Neumann, Thomas; Ohlsson, Sophie; Quickert, Stefanie; Ramirez, Giuseppe A; Rewerska, Barbara; Schett, Georg; Sinico, Renato A; Szczeklik, Wojciech; Tesar, Vladimir; Vukcevic, Damjan; Terrier, Benjamin; Watts, Richard A; Vaglio, Augusto; Holle, Julia U; Wallace, Chris; Smith, Kenneth G C.
Afiliación
  • Lyons PA; Department of Medicine, University of Cambridge School of Clinical Medicine, University of Cambridge, Cambridge Biomedical Campus, Cambridge, CB2 0QQ, UK.
  • Peters JE; Cambridge Institute for Therapeutic Immunology and Infectious Disease, Jeffrey Cheah Biomedical Centre University of Cambridge, Cambridge, CB2 0AW, UK.
  • Alberici F; Department of Medicine, University of Cambridge School of Clinical Medicine, University of Cambridge, Cambridge Biomedical Campus, Cambridge, CB2 0QQ, UK.
  • Liley J; BHF Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Strangeways Research Laboratory, Wort's Causeway, Cambridge, CB1 8RN, UK.
  • Coulson RMR; Health Data Research UK, Cambridge, UK.
  • Astle W; Department of Medicine, University of Cambridge School of Clinical Medicine, University of Cambridge, Cambridge Biomedical Campus, Cambridge, CB2 0QQ, UK.
  • Baldini C; Nephrology and Immunopathology Unit-ASST Santi Paolo e Carlo, San Carlo Borromeo Hospital, Milan, Italy.
  • Bonatti F; Dipartimento di Scienze della Salute, University of Milano, Milano, Italy.
  • Cid MC; Department of Medicine, University of Cambridge School of Clinical Medicine, University of Cambridge, Cambridge Biomedical Campus, Cambridge, CB2 0QQ, UK.
  • Elding H; Medical Research Council Biostatistics Unit, Cambridge Institute of Public Health, Cambridge Biomedical Campus, Forvie Site, Robinson Way, Cambridge, CB2 0SR, UK.
  • Emmi G; Department of Medicine, University of Cambridge School of Clinical Medicine, University of Cambridge, Cambridge Biomedical Campus, Cambridge, CB2 0QQ, UK.
  • Epplen J; BHF Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Strangeways Research Laboratory, Wort's Causeway, Cambridge, CB1 8RN, UK.
  • Guillevin L; Medical Research Council Biostatistics Unit, Cambridge Institute of Public Health, Cambridge Biomedical Campus, Forvie Site, Robinson Way, Cambridge, CB2 0SR, UK.
  • Jayne DRW; NHS Blood and Transplant, Long Road, Cambridge Biomedical Campus, Cambridge, UK.
  • Jiang T; Rheumatology Unit, University of Pisa, Pisa, Italy.
  • Gunnarsson I; Unit of Molecular Genetics, University Hospital of Parma, Via Gramsci 14, 43126, Parma, Italy.
  • Lamprecht P; Department of Autoimmune Diseases, Hospital Clínic, University of Barcelona, Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), CRB-CELLEX, Barcelona, Spain.
  • Leslie S; The National Institute for Health Research Blood and Transplant Unit in Donor Health and Genomics at the University of Cambridge, University of Cambridge, Strangeways Research Laboratory, Wort's Causeway, Cambridge, CB1 8RN, UK.
  • Little MA; Department of Human Genetics, The Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, CB10 1HH, UK.
  • Martorana D; Department of Experimental and Clinical Medicine, University of Firenze, Firenze, Italy.
  • Moosig F; Human Genetics, Ruhr University Bochum, Bochum, Germany.
  • Neumann T; Service de Médecine Interne, Hôpital Cochin, 75679, Paris Cedex 14, France.
  • Ohlsson S; Department of Medicine, University of Cambridge School of Clinical Medicine, University of Cambridge, Cambridge Biomedical Campus, Cambridge, CB2 0QQ, UK.
  • Quickert S; BHF Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Strangeways Research Laboratory, Wort's Causeway, Cambridge, CB1 8RN, UK.
  • Ramirez GA; Division of Rheumatology, Department of Medicine, Karolinska University Hospital, Karolinska Institute, Stockholm, Sweden.
  • Rewerska B; Department of Rheumatology and Clinical Immunology, University of Lübeck, 23562, Lübeck, Germany.
  • Schett G; Schools of Mathematics and Statistics, and BioSciences, and Melbourne Integrative Genomics, University of Melbourne, Parkville, VIC, 3010, Australia.
  • Sinico RA; Data Science, Murdoch Children's Research Institute, Parkville, VIC, 3052, Australia.
  • Szczeklik W; Trinity Health Kidney Centre, Trinity Translational Medicine Institute, Tallaght Hospital, Dublin, Ireland.
  • Tesar V; Unit of Molecular Genetics, University Hospital of Parma, Via Gramsci 14, 43126, Parma, Italy.
  • Vukcevic D; Rheumazentrum Schleswig-Holstein Mitte, Neumünster, Germany.
  • Terrier B; Department of Rheumatology, Immunology and Rehabilitation, Cantonal Hospital St. Gallen, St. Gallen, Switzerland.
  • Watts RA; Department of Nephrology, Division of Clinical Sciences, Lund University, Lund, Sweden.
  • Vaglio A; Department of Internal Medicine 3, Jena University Hospital, Jena, Germany.
  • Holle JU; Department of Internal Medicine 4 (Gastroenterology, Hepatology, and Infectious Diseases), Jena University Hospital, Jena, Germany.
  • Wallace C; Unit of Immunology, Rheumatology, Allergy and Rare Diseases, Università Vita Salute San Raffaele and IRCCS Ospedale San Raffaele, Milan, Italy.
  • Smith KGC; Jagiellonian University Medical College, Kraków, Poland.
Nat Commun ; 10(1): 5120, 2019 11 12.
Article en En | MEDLINE | ID: mdl-31719529
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Granulomatosis con Poliangitis / Anticuerpos Anticitoplasma de Neutrófilos / Predisposición Genética a la Enfermedad / Estudio de Asociación del Genoma Completo / Sitios Genéticos Tipo de estudio: Clinical_trials / Risk_factors_studies Límite: Humans Idioma: En Revista: Nat Commun Asunto de la revista: BIOLOGIA / CIENCIA Año: 2019 Tipo del documento: Article País de afiliación: Reino Unido Pais de publicación: Reino Unido
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Granulomatosis con Poliangitis / Anticuerpos Anticitoplasma de Neutrófilos / Predisposición Genética a la Enfermedad / Estudio de Asociación del Genoma Completo / Sitios Genéticos Tipo de estudio: Clinical_trials / Risk_factors_studies Límite: Humans Idioma: En Revista: Nat Commun Asunto de la revista: BIOLOGIA / CIENCIA Año: 2019 Tipo del documento: Article País de afiliación: Reino Unido Pais de publicación: Reino Unido