Your browser doesn't support javascript.
loading
The efficacy comparison of classic ketogenic diet and modified Atkins diet in children with refractory epilepsy: a clinical trial.
Poorshiri, Bita; Barzegar, Mohammad; Tahmasebi, Sanaz; Shiva, Shadi; Raeisi, Sina; Ebadi, Zakiyeh.
Afiliación
  • Poorshiri B; Pediatric Health Research Center, Tabriz University of Medical Sciences, Tabriz, Iran.
  • Barzegar M; Pediatric Health Research Center, Tabriz University of Medical Sciences, Tabriz, Iran. mm_barzegar@yahoo.com.
  • Tahmasebi S; Pediatric Health Research Center, Tabriz University of Medical Sciences, Tabriz, Iran.
  • Shiva S; Pediatric Health Research Center, Tabriz University of Medical Sciences, Tabriz, Iran.
  • Raeisi S; Pediatric Health Research Center, Tabriz University of Medical Sciences, Tabriz, Iran.
  • Ebadi Z; Pediatric Health Research Center, Tabriz University of Medical Sciences, Tabriz, Iran.
Acta Neurol Belg ; 121(2): 483-487, 2021 Apr.
Article en En | MEDLINE | ID: mdl-31677042
Dietary therapy has an important role in the therapeutic process in children suffering refractory epilepsy. There are two kinds of dietary therapy which are the most common in children with refractory epilepsy: The classic ketogenic diet (KD) and the modified Atkins diet (MAD). The purpose of the present study was to compare the efficacy, tolerability, and compliance of these two dietary therapies in the children who have refractory epilepsy during 6 months of treatment. From March 2017 to November 2018, 45 children aged 2-15 years who had refractory epilepsy were randomly allocated in KD or MAD group. The intervention period was 6 months in both groups. The frequencies of seizures were determined from parental reports and were compared between the groups. The patients with upper than 50% reduction in seizure frequency were deemed as responders to the diets. Twenty-four patients were assigned to the KD and 11 patients to the MAD. Overall, 45.8% of children treated with the KD and 45.5% of children treated with MAD had over than 50% response to the diet therapies. The difference was not statistically significant (P = 0.437). The MAD was more advantageous regarding better tolerability and fewer side effects. There is not much difference regarding the efficacy between the MAD and classic KD. The MAD with fewer side effects may be more suitable as the first line of dietary therapy in children with refractory epilepsy.
Asunto(s)
Palabras clave
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Dieta Cetogénica / Epilepsia Refractaria / Dieta Rica en Proteínas y Pobre en Hidratos de Carbono Tipo de estudio: Clinical_trials / Observational_studies / Prognostic_studies Límite: Adolescent / Child / Child, preschool / Female / Humans / Male Idioma: En Revista: Acta Neurol Belg Año: 2021 Tipo del documento: Article País de afiliación: Irán Pais de publicación: Italia
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Dieta Cetogénica / Epilepsia Refractaria / Dieta Rica en Proteínas y Pobre en Hidratos de Carbono Tipo de estudio: Clinical_trials / Observational_studies / Prognostic_studies Límite: Adolescent / Child / Child, preschool / Female / Humans / Male Idioma: En Revista: Acta Neurol Belg Año: 2021 Tipo del documento: Article País de afiliación: Irán Pais de publicación: Italia