SRSF2 Regulation of <i>MDM2</i> Reveals Splicing as a Therapeutic Vulnerability of the p53 Pathway.

Comiskey, Daniel F; Montes, Matías; Khurshid, Safiya; Singh, Ravi K; Chandler, Dawn S

SRSF2 Regulation of MDM2 Reveals Splicing as a Therapeutic Vulnerability of the p53 Pathway.

Comiskey, Daniel F; Montes, Matías; Khurshid, Safiya; Singh, Ravi K; Chandler, Dawn S.

Afiliación

Comiskey DF; Department of Pediatrics, The Ohio State University, Columbus, Ohio.
Montes M; Center for Childhood Cancer, The Research Institute at Nationwide Children's Hospital, Columbus, Ohio.
Khurshid S; Center for RNA Biology, Wexner Medical Center, The Ohio State University, Columbus, Ohio.
Singh RK; Department of Pediatrics, The Ohio State University, Columbus, Ohio.
Chandler DS; Center for Childhood Cancer, The Research Institute at Nationwide Children's Hospital, Columbus, Ohio.

Mol Cancer Res ; 18(2): 194-203, 2020 02.

Article en En | MEDLINE | ID: mdl-31662450

Asunto(s)

Carcinogénesis/metabolismo; Proteínas Proto-Oncogénicas c-mdm2/genética; Empalme del ARN/genética; Factores de Empalme Serina-Arginina/genética; Proteína p53 Supresora de Tumor/genética; Animales; Línea Celular Tumoral; Humanos; Ratones

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Empalme del ARN / Proteína p53 Supresora de Tumor / Proteínas Proto-Oncogénicas c-mdm2 / Carcinogénesis / Factores de Empalme Serina-Arginina Límite: Animals / Humans Idioma: En Revista: Mol Cancer Res Asunto de la revista: BIOLOGIA MOLECULAR / NEOPLASIAS Año: 2020 Tipo del documento: Article Pais de publicación: Estados Unidos

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