A new role for vault RNA-TEP1 complexes in mRNA production in trypanosomes.
J Biol Chem
; 294(43): 15575-15576, 2019 10 25.
Article
en En
| MEDLINE
| ID: mdl-31653772
Vault RNAs, found in vault ribonucleoprotein complexes, are known to be one of many types of small noncoding RNAs (ncRNAs), but their specific function is not known. A new study identifies a small ncRNA from Trypanosome brucei as a vault RNA (vtRNA) based on sequence analysis and its association with the canonical vault component TEP1. Down-regulation of T. brucei vtRNA impairs mRNA splicing in a permeabilized cell system, suggesting new roles for these enigmatic biomolecules.
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Trypanosoma brucei brucei
/
ARN Pequeño no Traducido
Idioma:
En
Revista:
J Biol Chem
Año:
2019
Tipo del documento:
Article
Pais de publicación:
Estados Unidos